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Adam Helberg - 07 Dec 2004 23:11 GMT
How do the topical anti flea products like Advantage work?

Do they get absorbed through the skin or distributed over the fur?

Adam
BarB - 08 Dec 2004 00:29 GMT
>How do the topical anti flea products like Advantage work?
>
>Do they get absorbed through the skin or distributed over the fur?
>
>Adam

From the manufacturer {Bayer}

Advantage stays on the surface of the pet’s skin for up to four weeks,
continuing to control fleas. It isn’t absorbed into the pet’s
bloodstream or internal organs. Advantage must be applied monthly
because that’s how often the pet’s skin cells are naturally shed.

BarB
Mike Rhino - 08 Dec 2004 01:23 GMT
> >How do the topical anti flea products like Advantage work?
> >
[quoted text clipped - 8 lines]
> bloodstream or internal organs. Advantage must be applied monthly
> because that's how often the pet's skin cells are naturally shed.

How does it get to the rest of the pet's skin from the neck?
~*Connie*~ - 08 Dec 2004 02:58 GMT
it gets into the sebaceous glands and is redistributed that way.

> > >How do the topical anti flea products like Advantage work?
> > >
[quoted text clipped - 10 lines]
>
> How does it get to the rest of the pet's skin from the neck?
BarB - 08 Dec 2004 03:48 GMT
>> >How do the topical anti flea products like Advantage work?
>> >
[quoted text clipped - 10 lines]
>
>How does it get to the rest of the pet's skin from the neck?

Again from Bayer:

How does Advantage travel over my pet without getting to the bloodstream?

Advantage is lipid or fat soluble, which means that it spreads to and is
locked onto the oil on the surface of every skin cell. Every skin cell has
a lipid or fatty membrane that attracts the lipid soluble Advantage to it.
Because Advantage stays on the skin and does not enter the bloodstream, it
kills fleas on contact. Fleas do not have to bite the pet or suck blood in
order to be killed.

Is Advantage constantly present on the skin of treated pets?

Advantage quickly distributes over the entire body surface of the pet,
from the top of the head to the tip of the tail. Within 12 hours of
application, Advantage has dried and locked onto the cells on the surface
of the pet's skin. This means that the flea can land anywhere on an
Advantage-treated pet, from the top of the head to the tip of the tail,
and it will still contact enough Advantage to be killed.

BarB
PatC - 09 Dec 2004 11:08 GMT
Hi
So why is it that I have found fleas on my cats just 2 weeks after applying
it? They were biting/scratching & when one of them got sleepy I had a bit of
a look & found 3 fleas in as many minutes. I must admit the fleas have never
got into the carpet etc. like they used to years ago pre-Advantage days, but
my cats still seem to have problems.
P

> >> >How do the topical anti flea products like Advantage work?
> >> >
[quoted text clipped - 32 lines]
>
> BarB
Ollie Clark - 09 Dec 2004 13:50 GMT
> BarB <pattist@earthlink.net> wrote in message
>> Again from Bayer:
[quoted text clipped - 23 lines]
> got into the carpet etc. like they used to years ago pre-Advantage days, but
> my cats still seem to have problems.

Perhaps your cats shed their skin quicker than normal. Perhaps Bayer have
been slightly optimistic in how long Advantage stays on the skin for
(can't imagine why). Perhaps the fleas had only just jumped on the cats
and hadn't died yet. Perhaps you didn't apply the Advantage properly.

You can get an injection from the vet which lasts for 6 months and, while
it doesn't kill the adult fleas, it stops the eggs they lay from hatching.
In addition to something which kills the adult fleas it can work well to
control fleas. Perhaps you should ask your vet about it.

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BarB - 09 Dec 2004 14:12 GMT
>Hi
>So why is it that I have found fleas on my cats just 2 weeks after applying
[quoted text clipped - 3 lines]
>my cats still seem to have problems.
>P

You may have new fleas coming in from outdoors or it may be because
new fleas have hatched out in the house. Fleas hatch depending on
conditions of heat and moisture. They can lie dormant in crevices in
floors and furniture for many months until conditions are just right.
If Advantage is working properly and you are using it on a regular
basis, those fleas should be dead in about 12 hours.

If you want even more protection, combine Advantage with an IGR
(insect growth regulator) like Program ( lufenuron) which is given
orally. That keeps fleas from laying viable eggs. I use Program for
my feral colony because it can be given in food. I also use it for
maintenance on my indoor fosters and only use Advantage if I see a
flea or I have a cat with flea dermatitis.

BarB
hamandcheese@betweentheknees.com - 09 Dec 2004 15:24 GMT
>So why is it that I have found fleas on my cats just 2 weeks after applying
>it? They were biting/scratching & when one of them got sleepy I had a bit of
>a look & found 3 fleas in as many minutes. I must admit the fleas have never
>got into the carpet etc. like they used to years ago pre-Advantage days, but
>my cats still seem to have problems.

If you got a lot of it on the fur instead on the skin it will be less
effective and wasted. I go very slow in applying as it doesn't flow
easily around the dense fur base.

-mhd
Philip Doolittle - 09 Dec 2004 16:09 GMT
> "PatC" wrote:
> So why is it that I have found fleas on my cats just 2 weeks after
[quoted text clipped - 6 lines]
> but
> my cats still seem to have problems.

Pat, remember that fleas thrive on furry mammals (generally pets, but you
qualify too), in textiles like carpeting, furniture, and bedding, and also
outside in the yard. Unless you erradicate all sources, they will continue
to jump onto your pet. And even with a good topical insecticide they will
live for awhile and bite.  Here are some things to consider in your quest to
eradicate fleas.

- Outdoor flea control is next to impossible.  Outside regular lawn
trimming, I recommend considering the outdoors a lost cause.  You can
chemically nuke the yard, but it's expensive, bad for the ecosystem in your
yard, and most likely not to healthy for your family either.

- Inside, a qualified pest control operator can apply a safe treatment to
your carpeting that will last 3-6 months.  This will prevent unwanted guests
from hopping off your pet and living in your house.  I believe our's uses
"precor" and we have been flea free despite 4 in/out cats and one in/out
dog.  Also, vacuum often and dispose of the bag in the outside trash can.
This is very important since the flea population is typically made up of 50%
eggs, 30% larvae, 15% pupae  and only 5% visible biting adults.

- On furry mammals, I have always been a big fan of FrontLine Plus for
several years. We used Advantage for awhile, but were not as pleased.  The
formulations are different and our vet recommends swapping periodically if
one becomes ineffective.  Here's what is in each:

         Frontline
           fipronil - Insecticide

         Frontline Plus
           fipronil - Insecticide
           methoprene - Insect Growth Regulator

         Advantage
           Imidacloprid - Insecticide

Finally, a word of caution.  You are applying pesticides to your pet and
there is some disagreement about the safety of doing so.  There is a good
article on the pros and cons of flea control in the Jan issue of our
newsletter.  It can be found at:
http://www.odordestroyer.com/news/story5/index.html

Sincerely,
Philip Doolittle
http://www.OdorDestroyer.com

See www.odordestroyer.com/newsletter for free monthly information to help
you and your pets. Latest articles:
- How to Select a Veterinarian.
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PatC - 10 Dec 2004 11:41 GMT
Hi
Yes I used to use Frontline.
I think I will go back to using it as Advantage does not seem to do as well

Thanks
P

> > "PatC" wrote:
> > So why is it that I have found fleas on my cats just 2 weeks after
[quoted text clipped - 56 lines]
> - How to Select a Veterinarian.
> - Great Gift Ideas for your Pets
Philip Doolittle - 10 Dec 2004 17:04 GMT
Also Frontline and Frontline Plus are different. The plus contains an IGR,
whereas the "regular" does not.

Sincerely,
Philip Doolittle
http://www.OdorDestroyer.com

> Hi
> Yes I used to use Frontline.
[quoted text clipped - 74 lines]
>> - How to Select a Veterinarian.
>> - Great Gift Ideas for your Pets
Ivor Jones - 10 Dec 2004 22:39 GMT
> Hi
> Yes I used to use Frontline.
[quoted text clipped - 3 lines]
> Thanks
> P

Have you tried Stronghold..? Similar to Advantage/Frontline but does
roundworm as well as fleas.

Ivor
BarB - 11 Dec 2004 16:59 GMT
>> Hi
>> Yes I used to use Frontline.
[quoted text clipped - 6 lines]
>Have you tried Stronghold..? Similar to Advantage/Frontline but does
>roundworm as well as fleas.

Stronghold is called Revolution in the US. (Chemical-Selamectin)
It also controls heartworms.

BarB
PatC - 15 Dec 2004 12:14 GMT
Thanks BarB
Never heard of it here in OZ
P

> >> Hi
> >> Yes I used to use Frontline.
[quoted text clipped - 11 lines]
>
> BarB
 
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