Perfectly healthy happy cat received a puncture wound in October. 6 weeks
of antibiotics and 4 weeks of steroid pills and the thing finally started to
heal. in mid January.
The vet shaved the cat's flank to get to the wound to drain it. That was
about six months ago. NONE of the fur in the entire shaved area has grown
back yet except for the hair right around the very edges of the wound. The
vet cannot explain it. Why won't the fur grow back in?
Right after the cat finished his second course of steroid, he began to
exhibit symptoms of diabetes--weight loss, excessive appetite, excessive
thirst, practically flooding his litter box.. His initial blood sugar test
was over 500. He is now on a prescription diet and was feeling better but
he is still losing weight. We will be back at the vet tomorrow for
additional testing.
Does anyone have any idea about the fur not growing?
Might the prolonged steroid treatment have caused some kind of hormonal
problem?
What do I need to discuss with the vet? I expect that insulin shots are in
our future here. Is there anything besides diabetes that could be causing
these problems?
Thanks!
Gene Royer - 29 Apr 2004 22:03 GMT
> Perfectly healthy happy cat received a puncture wound in October. 6 weeks
> of antibiotics and 4 weeks of steroid pills and the thing finally started to
[quoted text clipped - 22 lines]
>
> Thanks!
Steroids used in this case were in the *catabolic* class (no pun here)
instead of anabolic as the type used to build the body. Catabolic steroids
can cause lots of prollems, and one of them is diabetes. The other, of
course, results in a lesser ability of the animal to rebuilt its body. Slow
growing hair may be one of them.
I have a cat with a debilitating mouth disease that is only best treated
with twice monthly catabolic steroid injections. These cause him to have
diabetes, which we treat twice daily with type N human insulin. (He gets
four units with is 4/100 of a cc. Not much, but enough for a 13 pound cat.)
We had to shave each shoulder, right and left, to alternate his daily
injection; and the hair is very slow to grow back there.
In some cases, when the steroids are discontinued, the diabetes slowly
disappears; but now always. 500 is very high for a cat. I try to keep my
guy's glucose at 200 or thereabouts. And you might have to submit him to
weekly glucose testing strips until you get the feel for how much insulin to
give him regularly.
I watch my guy's drinking and urinating. When he starts going to the faucet
to get the drips, I know his glucose is going higher, and I compensate by
adding another unit at least one time a day. It is a learning process, and
I've pretty well mastered it after five years.
Catabolic steroids take a toll on the cat's appearance. You mentioned that
he was given the steroid in pill form. Pills have a less pronounced bell
curve than do injections, and many times, the oral application lasts longer
in the cat's system than do injections. But even after all traces of
steroids have vanished, the renal glands may not be willing to resume their
physiological job. --meaning that insulin might be needed, even in small
doses.
I would not be quick to start the insulin unless his glucose continues to
bump above 350 or so. And if you start, start very, very gradually with
extremely small doses.
This is prolly much more than you wanted to know.
--Geno
Pam Gibbs - 30 Apr 2004 02:24 GMT
Thank you!
When the vet gave me the pills I asked about the need to gradually decrease
the dosage and the vet said it would not be necessary. I asked again when
we got the second round of pills about gradually decreasing the dosage and
about side effects and was told that these things were not a concern with
cats. Then when the blood tests were done last week I asked again if
perhaps that four week course of steroids which was stopped suddenly had any
bearing on either the blood sugar problem or the hair problem and the vet
told me no. His attitude was basically "Why do you keep asking about that?"
I was actually reassured.
Your response is very helpful. I know now that I may need to find a new
vet, depending on how this one responds to questions that I now know I
should ask..
> > Perfectly healthy happy cat received a puncture wound in October. 6
> weeks
[quoted text clipped - 68 lines]
>
> --Geno
Rhonda - 30 Apr 2004 03:05 GMT
Our cat also got steroid-induced diabetes, I was so upset when I
realized it could have been avoided.
A very good place to get info is the message board at
www.felinediabetes.com. They will suggest home-testing the blood glucose
level. They are extremely helpful and have many knowledgeable people
checking in every day.
We started out at 1 unit of Humulin U once a day. Initial blood sugar
was over 400 and Bob was about 12 lbs. That worked well for 6 mos, then
we had to go to twice a day, trying different doses.
Good luck with your kitty.
Rhonda
> Perfectly healthy happy cat received a puncture wound in October. 6 weeks
> of antibiotics and 4 weeks of steroid pills and the thing finally started to
[quoted text clipped - 22 lines]
>
> Thanks!
Amy Gray - 30 Apr 2004 17:44 GMT
>What do I need to discuss with the vet? I expect that insulin shots are in
>our future here. Is there anything besides diabetes that could be causing
>these problems?
I would suggest finding another vet.
Marek Williams - 05 May 2004 02:42 GMT
>Might the prolonged steroid treatment have caused some kind of hormonal
>problem?
I am a human, not a cat, but I have some experience that may shed
light on this.
I have been diabetic since childhood. Normally I am well controlled
and have no problems.
About ten years ago I decided to get my eyes cut to cure myopia. The
surgeon did a terrific job -- 20-20 now. Immediately following the
surgery the surgeon prescribed drops that I was to put in my eyes. The
purpose was to retard healing so the eyes wouldn't scar. The drops
were a steroid.
The morning following the day of the surgery I discovered to my horror
that my BG was 450 mg/dL. I repeated the test and got the same answer.
I suspected that something had gone haywire with my meter, so I went
out to my car and got my other meter. Same results.
Then I called my doc and yelled for help. Doc was not in, so I wrote
down everything that had happened to me in the past month and faxed it
to him. Naturally, I included the eye surgery and the eye drops. He
called back half an hour later and said "no problem -- steroids always
do that." He recommended just increasing my insulin as necessary to
compensate as long as I was on the steroids. I did and after I went
off the steroids things went back to the way they were before.
The reason steroids don't do this to non-diabetics is that normal
people have 2-3 times the insulin-producing capacity they need. When
they go on steroids their pancreas just produces more to compensate.
>What do I need to discuss with the vet? I expect that insulin shots are in
>our future here.
Not if the diabetes was caused by the steroids. Once the cat is off
the steroids the insulin hormone levels will return to normal. Of
course, it is likely that your cat's pancreas is just barely able to
manage under normal conditions. Perhaps later in life it will become
necessary to go on insulin. But probably not at this point, once the
cat is off the steroids.
--
Bogus e-mail address, but I read this newsgroup regularly, so reply here.
Cheryl - 05 May 2004 02:49 GMT
> Not if the diabetes was caused by the steroids. Once the cat is off
> the steroids the insulin hormone levels will return to normal. Of
> course, it is likely that your cat's pancreas is just barely able to
> manage under normal conditions. Perhaps later in life it will become
> necessary to go on insulin. But probably not at this point, once the
> cat is off the steroids.
Marek, thank you for sharing your experience! Very interesting post!

Signature
Cheryl
/who has a cat on long-term Prednisone for IBD and is scared about
"unmasking" a diabetes predisposition.
Rhonda - 06 May 2004 05:27 GMT
Hmmmm. My only experience with diabetes and cats, was with steroids.
Our cat had a suspected food allergy (facial swelling and hair loss.) He
was put on steroids for a week. Three weeks later I noticed he has lost
a lot of weight and was soaking the litter box. Took him to the vet
again and he had lost 3 lbs and was diabetic. He was diabetic until his
death, 2 years later.
There are many other cats on the feline diabetes message board that have
steroid-induced diabetes. The internist vet said steroids were most
likely the trigger for our cat, he had type-b diabetes. She did say had
it not been the steroids then, something else could have caused it
later, it was just waiting for a trigger.
Rhonda
>>What do I need to discuss with the vet? I expect that insulin shots are in
>>our future here.
[quoted text clipped - 8 lines]
> --
> Bogus e-mail address, but I read this newsgroup regularly, so reply here.