My cat Felix is a 13 year old male. Around january of last year he had
laryngitis & trouble swallowing. I took him to the vet and
incidentally his protein level on labs was high. No one thought
anything of it. The laryngitis cleared up after a shot of steroid.
Around may/june I took him into the vet because his urination had
increased and his appetite had decreased. Labs showed elevated BUN/Cr
and he was diagnosed with Chronic renal failure. Looking back at the
labs the protein level was even more elevated but the vet didn't
address it. His ultrasound showed no abnormalities other than some
kidney changes consistent with chronic renal failure. X rays were
normal.
I treated him with subcutaneous fluids every other day, cyproheptatine
as an appetite stimulant and pepcid for vomiting.
I thought I should take him to a specialist to make sure I was doing
all the right things so I took him to the Animal Medical Center in
manhattan to see a nephrologist. She found his BUN/Cr even more
elevated so we changed the fluid schedule to every day 100 cc Subcut.
She also noticed the protein level being even more elevated so we did
a protein electrophoresis which showed he had a monoclonal gammopathy.
We did a bone marrow biopsy to rule out multiple myeloma and it was
negative. As were repeat ultrasounds and x-rays.
I continued to treat him for CHF with fluids, pecid, cyproheptadine &
now norvasc since he developed high blood pressure. On a follow up
exam his BUN/Cr was 130/4.9. I admitted him to the hospital for IV
fluids. They only decrease his BUN to 122 and his Creatine stayed the
same at 4.9. Also the vet mentioned the fluid might be pushing him
into heart failure because he developed a 4th heart sound. But she
didn't give him any heart meds. She decided it was time to address the
monoclonal gammopathy as it could be what was destroying the kidneys.
We started him on steroids (solumedrol) and antibiotic (baytril).
Almost immediately I noticed he started urinating less. Still more
than a normal cat but half of what he usually did. A few days later
his belly seemed distended and felt like it had fluid in it. And he
did not seem to feel well. Also a tremor/chill, which he had before,
had gotten worse.
I tried to call my vet at the AMC to see what to do & she never
returned my phone call or my email so I took him to a local vet that
someone recommended. He took labs (it was now 1 week later from when
he was admitted to the AMC and got IV fluid for 3 days) and his BUN/Cr
was 130/8.9.
Also he did an xray that indicates there is fluid in the abdomen.
He also found that he's anemic & has high phosphorus which my previous
vet, a nephrologist, neglected to tell me or treat. So we started him
and epogen & amphogel & gave him some vitamin B shots.
(Also he hasn't pooped for 8 days and the vet only suggested laxatone
which he won't eat.)
He suggested I admit him to the clinic for a few days of IV fluids. I
didn't want to admit him, the place is unstaffed at night and being
that he could die at any second I don't want him to die alone in a
cage without me with him. (it's a quality of life issue at the point,
he get terrified at the vet) (plus last week, 3 days of admission & iv
fluids didn't help so why put him through that again?) I brought him
in for some IV fluids in the day (I was going to take him home and
continue IV but moving him to the car blew the IV access). So we
decided to take him home, and bring him back the next day for more IV
fluids and see what happens. (he no longer is absorbing subcutaneous
fluids.)
So here I am, it's the next day and I'm writing this with my very sick
cat in my lap. Can anyone see anything I missed that can make any
difference? I've been frustrated with the discrepancies between how
the vets I've seen treat, (for example even in the local vets office
the 2 vets disagree about how much fluid he should get today, one says
250ml the other say that's too much because it will overload his
heart.)
Did the baytril make him worse?
Did the steroid make him worse?
Can anyone help me know what to do? I love him and it's killing me to
know I'm can't help him.
http://www.angelfire.com/stars/vs/Felix.html
victoria900@hotmail.com
>So here I am, it's the next day and I'm writing this with my very sick
>cat in my lap. Can anyone see anything I missed that can make any
[quoted text clipped - 7 lines]
>Can anyone help me know what to do? I love him and it's killing me to
>know I'm can't help him.
I'm sorry you're going through such a traumatic time. I've been there myself,
trying everything to no avail. Sometimes the cat has just had enough. Though I
realize this is painful advice, perhaps now is the time to consider the quality
of the remaining part of his life. Maybe you can just try to make him as
comfortable as possible with pain medication and give him lots of love for as
long as he has left. If he seems to be in pain or unhappy, maybe you can ask
your vet to visit your house for that last visit. Devout a few loving hours to
him and help him leave this world in a peaceful and loving manner. My prayers
are with you.
PawsForThought - 01 Nov 2003 20:47 GMT
>From: mmmaryinla@aol.comspam (Mary)
>>So here I am, it's the next day and I'm writing this with my very sick
>>cat in my lap. Can anyone see anything I missed that can make any
[quoted text clipped - 20 lines]
>him and help him leave this world in a peaceful and loving manner. My prayers
>are with you.
I'm sorry to hear about your cat too and I also have been there. Did the vet
recommend you giving subq's at home? Also, is your cat eating and going to the
bathroom? I think Mary is right, and it may be a time to consider the quality
of life for Felix. CRF is a horrible disease and takes way too many of our
feline friends. You may also want to check out Helen's website. I think it's
www.felinecrf.org but I may be wrong. Best wishes and healing purrs,
Lauren
________
See my cats: http://community.webshots.com/album/56955940rWhxAe
Raw Diet Info: http://www.holisticat.com/drjletter.html
http://www.geocities.com/rawfeeders/ForCatsOnly.html
Declawing Info: http://www.wholecat.com/articles/claws.htm
Warren O - 02 Nov 2003 01:44 GMT
>>From: mmmaryinla@aol.comspam (Mary)
>
[quoted text clipped - 31 lines]
>
> Lauren
Mary,
definitely check out the two main websites on CRF
http://www.felinecrf.org
http://www.felinecrf.com
and join the Yahoo Group for Feline CRF (there's a link to it on one of
the websites). I've been a member of the group for about two months and
they are wonderful people. Lots of good info and moral support.
Your cat's condition can be called "crashing" and many cats not only
survive, but go on to live high-quality lives for a few years. Some cats
go through more than one crash, but come out of it. Don't be surprised
if the IV therapy doesn't immediately bring the cat's numbers down
dramatically. Sometimes it'll take longer than a few days.
Best wishes for you and your cat,
Warren

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Brandy?Alexandre - 02 Nov 2003 04:07 GMT
Mary <mmmaryinla@aol.comspam> wrote in rec.pets.cats.health+behav:
> I'm sorry you're going through such a traumatic time. I've been
> there myself, trying everything to no avail. Sometimes the cat has
[quoted text clipped - 6 lines]
> Devout a few loving hours to him and help him leave this world in
> a peaceful and loving manner. My prayers are with you.
I was trying to think of the best way to say the same thing. Whether
something made the cat better or worse in end stage CRF isn't really
the point. Nothing is going to miraculously cure the cat and you just
have to say, "We're done here."

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Brandy??Alexandre?
http://www.swydm.com/?refer=BrandyAlx
Well, would you?
Joe Canuck - 04 Nov 2003 00:25 GMT
Brandy Alexandre wrote:
> the point. Nothing is going to miraculously cure the cat and you just
> have to say, "We're done here."
"We're done here"... how crude and cold.

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"Its the bugs that keep it running."
-Joe Canuck
PawsForThought - 04 Nov 2003 01:16 GMT
>From: Joe Canuck Joe_Canuck@Canada.ca
>Brandy Alexandre wrote:
>
>> the point. Nothing is going to miraculously cure the cat and you just
>> have to say, "We're done here."
>
>"We're done here"... how crude and cold.
I'm glad I'm not the only one who noticed this. What a strange way to put it.
________
See my cats: http://community.webshots.com/album/56955940rWhxAe
Raw Diet Info: http://www.holisticat.com/drjletter.html
http://www.geocities.com/rawfeeders/ForCatsOnly.html
Declawing Info: http://www.wholecat.com/articles/claws.htm
Warren O - 04 Nov 2003 17:56 GMT
>>From: Joe Canuck Joe_Canuck@Canada.ca
>
[quoted text clipped - 6 lines]
>
> I'm glad I'm not the only one who noticed this. What a strange way to put it.
"We're done here" might be a poor choice of words, but the PTS question
*is* a hard one and one that just about every pet owner will have to
deal with some time. You have to weigh a lot of different factors
(treatment options, cost, free time available to devote to care-giving,
etc.) at a time when you're obviously very upset. On the other hand,
sometimes there are nagging questions about "what if..." that rip you
apart if you PTS while there's still a chance for a good life.
I'm not looking forward to making that decision with my early-stage CRF
cat, but I read somewhere that a decision made with love can't be wrong.
I agree with that. If you're doing what you believe is best for the cat,
that's all that matters. Screw what other people think.
And everyone deals with grief a little differently. Some prefer to sever
emotional ties quickly, others prefer to let go more slowly. "We're done
here" might be Brandy's way of dealing with this difficult situation.
Just my two cents,
Warren

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Joe Canuck - 04 Nov 2003 21:13 GMT
> emotional ties quickly, others prefer to let go more slowly. "We're done
> here" might be Brandy's way of dealing with this difficult situation.
Hang around Warren, you'll find "Brandy" has a different way of dealing
with a lot of things.
Besides, the post was meant for the original poster who might not have
appreciated the phrase... a little sensitivity was in order.

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"Its the bugs that keep it running."
-Joe Canuck
> My cat Felix is a 13 year old male. Around january of last year he had
> laryngitis & trouble swallowing. I took him to the vet and
> incidentally his protein level on labs was high. No one thought
> anything of it. The laryngitis cleared up after a shot of steroid.
>
> Around may/june I took him into the vet because his urination had
*> increased and his appetite had decreased. Labs showed elevated BUN/Cr
> and he was diagnosed with Chronic renal failure. Looking back at the
**> labs the protein level was even more elevated
I think his azotemia could be secondary to his elevated protein levels and
not necessarily from primary CRF. High levels of protein in the blood
makes the blood thicker (hyper?viscosity) > which in turn decreases renal
perfusion and oxygen to the kidneys (renal hypoxia) -- which can cause the
kidneys to fail.
but the vet didn't
> address it. His ultrasound showed no abnormalities other than some
> kidney changes consistent with chronic renal failure. X rays were
[quoted text clipped - 6 lines]
> all the right things so I took him to the Animal Medical Center in
> manhattan to see a nephrologist.
Try to get touch with Dr. Ann Hohenhaus at AMC and ask her to review the
results of the serum protein electrophoresis and your cat's chart.
She found his BUN/Cr even more
> elevated so we changed the fluid schedule to every day 100 cc Subcut.
> She also noticed the protein level being even more elevated so we did
**> a protein electrophoresis which showed he had a monoclonal gammopathy.
> We did a bone marrow biopsy to rule out multiple myeloma and it was
> negative. As were repeat ultrasounds and x-rays.
> I continued to treat him for CHF with fluids, pecid, cyproheptadine &
> now norvasc since he developed high blood pressure. On a follow up
> exam his BUN/Cr was 130/4.9. I admitted him to the hospital for IV
> fluids. They only decrease his BUN to 122 and his Creatine stayed the
**> same at 4.9. Also the vet mentioned the fluid might be pushing him
> into heart failure because he developed a 4th heart sound.
Could be. But I think his CRF is also secondary to hyper?viscosity -- due to
the very heavy workload on the heart from continuously pumping very thick
blood. Also, monoclonal proteins in the blood draws fluid into the blood
which can cause hypervolemia > which can also lead to CHF. This is what
happened in one of our dogs who had monoclonal gammopathy - but his MG was
caused by chronic lymphocytic leukemia. Fortunately, CLL is rare in cats -
so I don't think you have to worry about that.
But she
> didn't give him any heart meds. She decided it was time to address the
**> monoclonal gammopathy as it could be what was destroying the kidneys.
Absolutely! .... and causing his CHF .... and his worsening tremor. The
number *one* complication of monoclonal gammopa?thies is the hyperviscosity
syndrome - which can also seriously affect the eyes and the CNS.
> We started him on steroids (solumedrol) and antibiotic (baytril).
> Almost immediately I noticed he started urinating less. Still more
> than a normal cat but half of what he usually did. A few days later
> his belly seemed distended and felt like it had fluid in it. And he
> did not seem to feel well.
**Also a tremor/chill, which he had before,
> had gotten worse.
> I tried to call my vet at the AMC to see what to do & she never
> returned my phone call or my email so I took him to a local vet that
[quoted text clipped - 31 lines]
> Can anyone help me know what to do? I love him and it's killing me to
> know I'm can't help him.
I think you should focus your attention on finding the cause of the
monoclonal gammopathy and elevated protein - That would be my *first*
priority because *all* of the symptoms you've described can occur secondary
to elevated protein - including signs of CRF and CHF and even his tremor.
Keep the faith!
Best of luck.
Phil.
> http://www.angelfire.com/stars/vs/Felix.html
> victoria900@hotmail.com