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Cat Forum / Health and Behavior / July 2005

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Need Revolution Dosage Help

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CatNipped - 11 Jul 2005 15:12 GMT
I need to order Revolution from petmeds.com.  I'm going to order the "large
dog" dosage because that's the best buy.  Can anyone here tell me what
dosages I need to break that down into to get the correct amount for 4 cats
(2 cats at 7 pounds, 1 cat at 9 pounds, and 1 cat at 15 pounds)?

Hugs,

CatNipped
Steve G - 11 Jul 2005 15:54 GMT
> I need to order Revolution from petmeds.com.  I'm going to order the "large
> dog" dosage because that's the best buy.  Can anyone here tell me what
> dosages I need to break that down into to get the correct amount for 4 cats
> (2 cats at 7 pounds, 1 cat at 9 pounds, and 1 cat at 15 pounds)?

IIRC, it's 15mg per cat (from memory).

(Checking). No, apparently it's 45mg:
http://www.revolution4dogs.com/PAHimages/compliance_pdfs/US_EN_RV_compliance.pdf

Concentrations of selamectin are greater in the large dog doses so
obviously you'll need to take that into a/c when splitting the dose.

Steve.
CatNipped - 11 Jul 2005 16:19 GMT
> > I need to order Revolution from petmeds.com.  I'm going to order the "large
> > dog" dosage because that's the best buy.  Can anyone here tell me what
[quoted text clipped - 4 lines]
>
> (Checking). No, apparently it's 45mg:

http://www.revolution4dogs.com/PAHimages/compliance_pdfs/US_EN_RV_compliance.pdf

> Concentrations of selamectin are greater in the large dog doses so
> obviously you'll need to take that into a/c when splitting the dose.
>
> Steve.

Thanks Steve.  But I'm terrible in math, and worse in chemistry.  Is this
saying that I should .37mL of 120 mg/mL potency per cat?

Hugs,

CatNipped
Steve G - 11 Jul 2005 17:01 GMT
(...)

> Thanks Steve.  But I'm terrible in math, and worse in chemistry.  Is this
> saying that I should .37mL of 120 mg/mL potency per cat?

Bloody Mensans. Yes, that's quite correct - the concentration of large
dog doses is *double* that of the cat doses, so you should use half the
amount (22.5mg of the active, i.e., 0.375ml). Dunno if the money saved
is worth the pissing about with syringes etc. anyway?

(Actually, I misread that PDF the first time - I read the mg column as
the total weight of the solution, not the weight of the active. Doh).

S.
CatNipped - 11 Jul 2005 17:43 GMT
> (...)
> >
[quoted text clipped - 5 lines]
> amount (22.5mg of the active, i.e., 0.375ml). Dunno if the money saved
> is worth the pissing about with syringes etc. anyway?

I never claimed to be *smart*, just really good at taking tests and word
puzzles!  ;>

I already have syringes here, so I won't have to buy those, and the prices
are significantly lower with the large dog dosages.  Let's see if I've done
this right, quoted from petmeds.com:

3 cat dosages (.75mL of 60 mg/mL potency each) is $36.99 US
3 large dog dosages (3.0mL of 120 mg/mL potency each) (or 24 cat dosages @
.75mL of 60 mg/mL potency each) is $59.99 US

So, for cat purchase it comes down to $16.44 US per mL; and for large dog
purchase it comes down to $3.33 US per mL (since you have to halve it for
potency).  Or, to put it in price per dosage, it's: cat purchase $12.33 US
per dose; and for large dog purchase it's $2.50 US per dose. That's quite a
difference - or did I screw up the math?

So, I could spend $36.99 US for 3 doses, or I could spend $59.99 US for 24
doses, right?

Hugs,

CatNipped

> (Actually, I misread that PDF the first time - I read the mg column as
> the total weight of the solution, not the weight of the active. Doh).
>
> S.
CatNipped - 11 Jul 2005 17:56 GMT
> > (...)
> > >
[quoted text clipped - 30 lines]
>
> CatNipped

Actually, I just found the large dog dosage of Revolution at
Petscriptions.com for $49.25 US - so that's an even better price.

Hugs,

CatNipped
Steve G - 11 Jul 2005 18:06 GMT
(...)

> 3 cat dosages (.75mL of 60 mg/mL potency each) is $36.99 US
> 3 large dog dosages (3.0mL of 120 mg/mL potency each) (or 24 cat dosages @
[quoted text clipped - 5 lines]
> per dose; and for large dog purchase it's $2.50 US per dose. That's quite a
> difference - or did I screw up the math?

No, that's right. (2.25ml of cat Revo at $36.99 versus the equivalent
of 36ml of Cat Revo at $59.99).

Hm - maybe that's indeed a saving worth having, would be c.$180/year
for me, basically the cost of a couple of vet checkups or half a year's
cat food. Would need a suitable container to store the split larger
dose...

> So, I could spend $36.99 US for 3 doses, or I could spend $59.99 US for 24
> doses, right?

Indeed.

I assume there's no problem buying a dog dose with a cat prescription?

S.
CatNipped - 11 Jul 2005 18:07 GMT
> (...)
> >
[quoted text clipped - 24 lines]
>
> S.

I don't think you need a vet's prescription for flea medication when buying
online - but I've never done so, so I don't know.  I'm sure, though, if you
talk to your vet about the price differences (stressing that you could
afford more of his/her services if you save  the money) he/she would go
along with it.

Hugs,

CatNipped
Steve G - 11 Jul 2005 18:21 GMT
(...)

> I don't think you need a vet's prescription for flea medication when buying
> online - but I've never done so, so I don't know.

You do for Revolution (you'll need to get your vet to fax the
prescription).

>  I'm sure, though, if you
> talk to your vet about the price differences (stressing that you could
> afford more of his/her services if you save  the money) he/she would go
> along with it.

Yeah, apart from the fact that they'd be stiffed out of a couple of
hundred $/year, for many years...

I suppose I could say I need to save the cash otherwise I won't be able
to afford the vet fees for removal of the lumps from my rat's tumerous
bod (write me a prescription, or the rat gets it! Can't see that one
washing. Write me a prescription, or I'll boil this baby bunny! Write
me a prescription or I'll maliciously poke my cat in the belly with a
sharpened fig! yeah!).

S.
CatNipped - 11 Jul 2005 18:42 GMT
> (...)
> >
[quoted text clipped - 20 lines]
>
> S.

OK, Petscriptions.com is asking for a vet, but Petmeds.com is not.

Hugs,

CatNipped
Steve G - 11 Jul 2005 19:18 GMT
(...)

> OK, Petscriptions.com is asking for a vet, but Petmeds.com is not.

It is, you know - check the RxHelp button on the Revolution pages.

S.
CatNipped - 11 Jul 2005 20:27 GMT
> (...)
> >
[quoted text clipped - 3 lines]
>
> S.

Ah, OK.  I didn't want to send in the order without talking it over with my
husband first, so I didn't go completely through checkout - just got to the
page where it asked for my credit card number.

I don't think my vet will give the approval for a large dog (it's a cats
only clinic) - the vet tech didn't seem to think she would, but I haven't
talked to the vet about it yet.

Hugs,

CatNipped
BarB - 13 Jul 2005 00:37 GMT
>I need to order Revolution from petmeds.com.  I'm going to order the "large
>dog" dosage because that's the best buy.  Can anyone here tell me what
[quoted text clipped - 4 lines]
>
>CatNipped

You have 38 pounds of cat to treat at a minimum of 2.7 mg per pound
so you need the size containing at least 103 mg of drug. That's going
to be the red box.  Give the 15 pound cat .35 ml, the 9 pounder .25
and the smaller cats .2 ml.  

Actual figures:

 minimum dose 2.7 mg per lb / 120mg per ml x 15 lb cat = .34 ml
 minimum dose 2.7 mg per lb / 120mg per ml x  9 lb cat = .20 ml
 minimum dose 2.7 mg per lb / 120mg per ml x  7 lb cat = .16 ml  
   
Weight(lb) Package  mg per tube   Potency(mg/mL)  volume (mL)
          color  

20.1-40    Red       120 mg           120           1.0
40.1-85    Teal      240 mg           120           2.0
85.1-130   Plum      120+240 mg       120           3.0



Revolution™ -- U.S. Prescribing Information

              Topical Parasiticide For Dogs and Cats

         
DESCRIPTION:
Revolution (selamectin) Topical Parasiticide is available as a
colorless to yellow,ready to use solution in single dose tubes for
topical(dermal) treatment of dogs and cats six weeks of age and
older. The content of each tube is formulated to provide a minimum of
2.7 mg/lb (6 mg/kg) of body weight of selamectin. The chemical
composition of selamectin is (5Z,25S)-25-cyclohexyl-
4'-O-de(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-5-demethoxy-
25-de(1-methylpropyl)-22,23-dihydro-5-hydroxyiminoavermectin A1a.

INDICATIONS:
Revolution kills adult fleas and prevents flea eggs from hatching for
one month and is indicated for the prevention and control of flea
infestations (Ctenocephalides felis), prevention of heartworm
disease caused by Dirofilaria immitis, and the treatment and control
of ear mite(Otodectes cynotis) infestations in dogs and cats.
Revolution also is indicated for the treatment and control of
sarcoptic mange (Sarcoptes scabiei) and for the control of tick
(Dermacentor variabilis) infestations in dogs, and the treatment of
intestinal hookworm (Ancylostoma tubaeforme) and roundworm
(Toxocara cati) infections in cats. Revolution is recommended for use
in dogs and cats six weeks of age and older.


DOSAGE:
The recommended minimum dose is 2.7 mg selamectin per pound (6 mg/kg)
of body weight.

BarB
CatNipped - 13 Jul 2005 02:41 GMT
> >I need to order Revolution from petmeds.com.  I'm going to order the "large
> >dog" dosage because that's the best buy.  Can anyone here tell me what
[quoted text clipped - 55 lines]
>
> BarB

Thanks!  Great information!!

Hugs,

CatNipped
 
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