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Cat Forum / Health and Behavior / July 2005

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Hyperthyroidism became hypothyroidism

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Diadia - 06 Jul 2005 21:44 GMT
>From too much thyroid to too little.

Treatment with radioactive iodine worked too well on my cat.

My hope of having a well cat who doesn't need a pill has just
evaporated.

I was never presented this as a possitibility.  But now faced with the
reality, I want other to know it can and did happen.

d.
Mary - 06 Jul 2005 21:46 GMT
> >From too much thyroid to too little.
>
[quoted text clipped - 5 lines]
> I was never presented this as a possitibility.  But now faced with the
> reality, I want other to know it can and did happen.

Oh no. So now you have to give your cat thyroid every day?
Phil P. - 06 Jul 2005 22:08 GMT
> >From too much thyroid to too little.
>
[quoted text clipped - 5 lines]
> I was never presented this as a possitibility.  But now faced with the
> reality, I want other to know it can and did happen.

This is not unusual.  After radioiodine tx,  many cats go through a period
of subclinical hypothyroidism that's almost always asymptomatic and usually
doesn't require any therapy in the vast majority of cats.  During this short
period, TSH (thyroid-stimulating hormone) secretion resumes again, the
normal, atrophied thyroid tissue becomes functional again, and the cat then
becomes euthyroid.  In the very cases where permanent hypothyroidism does
occur, its usually several months after I-131 tx.  How long ago did your cat
receive I-131 tx?

Phil
Diadia - 07 Jul 2005 14:41 GMT
3 months.

What's my prognosis now?

d.
Phil P. - 08 Jul 2005 05:09 GMT
> 3 months.
>
> What's my prognosis now?

You're in the delicate range- T4 could still go up.  I would monitor her T4
levels every month for the next few months and if she's still hypothyroid
after 6 months, monitor every other month for a few months.  You don't need
a full chemistry- just T4.

Best of luck,

Phil.
Phil P. - 08 Jul 2005 06:29 GMT
> 3 months.
>
> What's my prognosis now?

You're in the delicate range- T4 could still go up.  I would monitor her T4
levels every month for the next few months and if she's still hypothyroid
after 6 months, monitor every other month for a few months.  You don't need
a full chemistry- just T4.

Best of luck,

Phil.
Candace - 06 Jul 2005 22:08 GMT
> >From too much thyroid to too little.
>
[quoted text clipped - 7 lines]
>
> d.

This happened to my friend, not her cat, *her*.  I think it's always a
possibility.  Sorry about your kitty; hopefully the meds will work well
but it is a drag that you have to continue to pill her.

Candace
Kitkat - 06 Jul 2005 22:34 GMT
>>>From too much thyroid to too little.
>>
[quoted text clipped - 10 lines]
> This happened to my friend, not her cat, *her*.  I think it's always a
> possibility.

I think that thyroids are just that tricky. That is what I have
discovered about them since I had to become a thyroid expert. ;)

> Sorry about your kitty; hopefully the meds will work well
> but it is a drag that you have to continue to pill her.

Yes. Best of luck with kitty! Purrs! :)
Pam
sculley - 07 Jul 2005 02:16 GMT
There is a topical you can use instead of the pill which may or may not
coause stomache problems ,you just rub it in it's ear . Ask your vet to find
a pharm. that will mix it .

>> >From too much thyroid to too little.
>>
[quoted text clipped - 13 lines]
>
> Candace
Diadia - 07 Jul 2005 14:41 GMT
Thanks for the tip.

I am still waiting for a doctor from the iodine treatment center to
call me.  

d.
Diadia - 07 Jul 2005 23:46 GMT
I am still waiting.  My personal vet said I should call radio cat
vetinary hospital, but the doctor in 24 hours hasn't returned my call.
This is in northern
Virginia.  My initial impression was that this was a professional
outfit.  Now I am not so sure.

When I called to voice concern, I got a defensive posture from the
receptionist, who immediately wanted to spin the disappointing results
into something positve.  All I want is some useful advice as to what I
do next.

The numbers used to chart the level of thyroid in a cat are confusing,
and if anyone can guide me here, I would appreciate it.

But it seems for more than a thousand bucks, the doctor could talk to
me when the results are less than terrific.

d.
Phil P. - 08 Jul 2005 05:12 GMT
> I am still waiting.  My personal vet said I should call radio cat
> vetinary hospital, but the doctor in 24 hours hasn't returned my call.
> This is in northern
> Virginia.  My initial impression was that this was a professional
> outfit.  Now I am not so sure.

When he finally returns your call, ask him what was the dose of  I-131.
When  a cat develops permanent hypothyroidism (longer than 3-4 months after
tx) its usually because the cat received a large (too large) dose. The
rational behind large doses is to destroy all the hyperplastic (adenomatous)
thyroid tissue in one shot.  Large doses are necessary in cats with thyroid
carcinomas- only about 2% of hyperthyroid cats have malignant thyroid
carcinomas.  The large doses certainly cures hyperthyroidism and destroys
hyperplastic and cancerous thyroid tissue anywhere in the body- but they
also greatly increase the risk of hypothyroidism.  Since you paid for the
I-131, you have a right to know how much was used.

> When I called to voice concern, I got a defensive posture from the
> receptionist, who immediately wanted to spin the disappointing results
[quoted text clipped - 3 lines]
> The numbers used to chart the level of thyroid in a cat are confusing,
> and if anyone can guide me here, I would appreciate it.

"Normal" T4 can be confusing! The reference range for T4 in our lab is 0.8 -
2.0 mcg/dl- but we've had normal cats with serum T4 over 2.0- but always
less than 5.0 mcg/dl.   What is your lab's reference range and what is your
cat's level?

Phil
Phil P. - 08 Jul 2005 06:30 GMT
> I am still waiting.  My personal vet said I should call radio cat
> vetinary hospital, but the doctor in 24 hours hasn't returned my call.
> This is in northern
> Virginia.  My initial impression was that this was a professional
> outfit.  Now I am not so sure.

When he finally returns your call, ask him what was the dose of  I-131.
When  a cat develops permanent hypothyroidism (longer than 3-4 months after
tx) its usually because the cat received a large (too large) dose. The
rational behind large doses is to destroy all the hyperplastic (adenomatous)
thyroid tissue in one shot.  Large doses are necessary in cats with thyroid
carcinomas- only about 2% of hyperthyroid cats have malignant thyroid
carcinomas.  The large doses certainly cures hyperthyroidism and destroys
hyperplastic and cancerous thyroid tissue anywhere in the body- but they
also greatly increase the risk of hypothyroidism.  Since you paid for the
I-131, you have a right to know how much was used.

> When I called to voice concern, I got a defensive posture from the
> receptionist, who immediately wanted to spin the disappointing results
[quoted text clipped - 3 lines]
> The numbers used to chart the level of thyroid in a cat are confusing,
> and if anyone can guide me here, I would appreciate it.

"Normal" T4 can be confusing! The reference range for T4 in our lab is 0.8 -
2.0 mcg/dl- but we've had normal cats with serum T4 over 2.0- but always
less than 5.0 mcg/dl.   What is your lab's reference range and what is your
cat's level?

Phil
clfr@adelphia.net - 07 Jul 2005 01:45 GMT
> >From too much thyroid to too little.
>
[quoted text clipped - 7 lines]
>
> d.

Thanks; interesting data point.

One of my cats had thyroid surgery, since it was her only real option
at the time.  There was no radioactive iodine treatment avaialble
within a reasonable distance from here then, & remaining on Tapazole
was contraindicated for her, since she had chronic liver disease.  She
eventually went hypo-T post-surgery, & then took thyroxine - which did
work & produced normal results on her thyroid bloodwork.

Cathy
 
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