Home | Contact Us | FAQ | Search & Site Map | Link to Us
Sign In | Join | Other 45 Sites in Network
Home
Discussion GroupsGeneral TopicsCat AnecdotesHealth and BehaviorRescue
CatKB.com
Contact UsLink To UsSearch & Site Map

Cat Forum / Health and Behavior / October 2003

Tip: Looking for answers? Try searching our database.

Phil, Helen, Someone....Please Help

Thread view: 
Enable EMail Alerts  Start New Thread
Thread rating: 
Mavalon - 13 Sep 2003 22:30 GMT
My Kitty was diagnosed with kidney failure.  Unsure if it's chronic or
acute.  Doesn't really matter as the vet says his numbers are
extremely high and after 72 hours of IV hospitalization they got
worse.  Vet says he's going to die soon and let him live out his last
couple of weeks at home.  We're heartbroken and still want to fight
it.  We think our cat has some fight left in him as well.  Here's a
bit of a history:

6 days ago - noticed symptoms & brought him into vet
5 days ago - blood tests came back with BUN 41.1, Creatinine 709 and
Phosphorus 2.50

Kept him hospitalized for 3.5 days on IV fluid and force fed low
protein food -he will not eat on his own

Brought him home from vet last night and waiting for 2nd blood test
results.  He was happy to be home, very tired but still didn't eat.
Force fed him this morning.  No vomitting. Gave 120 ml lactate ringers
this morning.  Vet called and said prognosis is very bad.  His levels
are up - BUN 47.7, Creatinine 927 and Phosphorus 3.09. Vet says keep
doing what I'm doing, but he will die very soon.

Did more reading on the internet and discovered phosphorus binders and
appetite stimulants.  Called vet back and said I wanted to try these
on him.  She agreed and wrote prescription.  I just gave him his first
dose of Periactin 2MG.  I'm supposed to give him 5MG Novo-Famotidine
every 24 hrs.  I'm waiting to see if Periactin does anything for him.

I'm just not ready to give up on this cat.  He's only 5 years old. We
will give up when he lets us know he's had enough. Before I went to
pick up his prescriptions, thought I'd try some salmon.  I sprinkled a
bit of garlic powder on it and much to my surpise he sniffed, then had
a couple of small nibbles. This felt so amazing as I had just finished
drying my puffy, red eyes after hearing the vet's prognosis.

What do you all think?  Am I fighting a hopeless battle?  Just this
morning he was perched on his post excitedly watching the birds. Is
there anything more I can do for him?  What do you think of his levels
and the fact they got worse after 3 days of IV?

Broken-hearted
PawsForThought - 13 Sep 2003 23:07 GMT
>From: mavalon2003@yahoo.com  (Mavalon)

>I just gave him his first
>dose of Periactin 2MG.  I'm supposed to give him 5MG Novo-Famotidine
>every 24 hrs.  I'm waiting to see if Periactin does anything for him.
>
>I'm just not ready to give up on this cat.  He's only 5 years old.

I'm so sorry to hear about your cat.  My last cat was given Periactin too and
it did work for a while.  But my cat was 17 years old.  

>Before I went to
>pick up his prescriptions, thought I'd try some salmon.  I sprinkled a
>bit of garlic powder on it and much to my surpise he sniffed, then had
>a couple of small nibbles. This felt so amazing as I had just finished
>drying my puffy, red eyes after hearing the vet's prognosis.

That's good!  The smellier you can make the food, the better.  You might want
to try sprinkling some Parmesan cheese on the food.  I know this worked with my
cat.

Best wishes for your kitty's recovery,

Lauren
________
See my cats:  http://community.webshots.com/album/56955940rWhxAe
Raw Diet Info: http://www.holisticat.com/drjletter.html
http://www.geocities.com/rawfeeders/ForCatsOnly.html
Declawing Info: http://www.wholecat.com/articles/claws.htm
rrb_041303 - 13 Sep 2003 23:11 GMT
Mavalon said:
> My Kitty was diagnosed with kidney failure.  Unsure if it's chronic or
> acute.  Doesn't really matter as the vet says his numbers are
[quoted text clipped - 37 lines]
>
> Broken-hearted

I don't have any advice other than offering my best wishes to you both,
& to suggest that you post to alt.med.veterinary as well.

rrb
Phil P. - 13 Sep 2003 23:45 GMT
> My Kitty was diagnosed with kidney failure.  Unsure if it's chronic or
> acute.  Doesn't really matter as the vet says his numbers are
[quoted text clipped - 37 lines]
>
> Broken-hearted

Is he urinating?  Did the vet check him for a urinary tract obstruction?  A
complete (or nearly complete): urinary tract obstruction produces a
pathophysiologic state equivalent to oliguric acute renal failure.  An
obstruction will also cause the BUN/Cr to rise especially after fluid
therapy.

A obstruction can occur anywhere in the urinary tract.  In male cats they
occur most commonly in the urethra - where it narrows, almost like a funnel,
right where it passes over the pelvis into the penis.  I doubt your vet is
equipped for contrast urethrography, however, most uroliths are radiodense
and visible on x-rays -- although ultrasounds would be the ideal choice for
locating an obstruction.

If an obstruction is ruled out *definitively* and he's able to urinate
adequately, diuretics (furosemide, a/k/a Lasix) are usually given to
stimulate urinary output, which should help speed up the excretion of renal
toxins and ezcessive electroltyes - especially potassium which can result in
life-threatening hyperkalemia. . Intense diuresis maybe necessary.

There's another alternative - but I don't know your vet's level of
expertise. The alternative is a form of dialysis called peritoneal dialysis
that can be used to clean the blood.  Its not as bad as it sounds.  In
short, it involves placing a catheter in your cat's abdomen and filling the
abdominal cavity with fluid and then draining it out after the waste
products have filtered into the fluid.  This technique can be quite
effective and reverse a uremic crisis.  The catheter can be left in and you
can perform the procedure at home.

My best advice would be to take your cat to the emergency room of a
veterinary university hospital if there's one within range.  They would be
fully equipped to handle this crisis.

If you don't live near a vet university, go to

http://www.acvim.org/Kittleson/search.htm

and do a search for an internal medicine Diplomate/Specialist in your area.
American College of Veterinary Internal Medicine Diplomates are about the
best there is.

If you can't find an ACVIM specialist in your area, my second choice would
be an ABVP Diplomate/Feline Specialist (American Board of Veterinary
Practitioners).

Go to

http://www.abvp.com/diplosearch1.htm http://www.abvp.com/

I'm sorry I can't be more helpful.

I wish you the very best of luck.

Phil.
blkcatgal - 14 Sep 2003 04:35 GMT
Check out felinecrf.com for some useful information.  Also, you may want to
join the Feline CRF support group at groups.yahoo.com.

Sue

> My Kitty was diagnosed with kidney failure.  Unsure if it's chronic or
> acute.  Doesn't really matter as the vet says his numbers are
[quoted text clipped - 37 lines]
>
> Broken-hearted
Helen - 14 Sep 2003 12:29 GMT
> My Kitty was diagnosed with kidney failure.  Unsure if it's chronic or
> acute.  Doesn't really matter as the vet says his numbers are
[quoted text clipped - 37 lines]
>
> Broken-hearted

[I'm having trouble posting this, so I'm going to e-mail it too]

I'm sorry to hear about your boy. The rise in numbers might be related to a
blockage or stone of some kind, did the vet check for this at all? I'm also
not sure whether this is acute or chronic renal failure.

I cannot tell you whether your boy will make it. However, the fact that he
is alert and interested in birds appears to me to be a good thing. His
bloodwork is bad, but it's not as bad as my Thomas's was at diagnosis; in US
values, your boy has BUN of 133, whereas my Thomas had BUN of 241. Thomas
was on IV for four solid days and nights, yet after that his BUN was exactly
the same, 241. I brought him home to die, but with sub-Qs we were able to
gradually reduce his numbers and win back his quality of life for him. There
is just no telling which cat will make it and which cat won't; but I think
it is always worth trying treatments, because even if they don't prolong
life, they should at least make the cat more comfortable; and it can help
you to know you've tried everything you can.

I would stop the garlic immediately. It belongs to the onion family, and
onion causes Heinz body anaemia in cats. The jury is out on whether garlic
does the same, but I wouldn't take the risk in a cat who is already sick.

I also wouldn't be forcing the cat to eat prescription food. He feels bad,
so I'd let him eat whatever he wants right now (giving him phosphorus
binders if it's non-prescription food). You can try the prescription food
later if he stabilises, but right now it's more important that he eats. The
famotidine should help, though you appear to be giving a high dose. I'm not
sure what novo-famotidine is, but the usual dose for famotidine in the form
of Pepcid AC is 2.5 mg, once every other day to start with. But of course
you should be guided by your vet on dosages (I'm assuming your vet suggested
these treatments, BTW).

Incidentally, you don't mention which phosphorus binder you are using, but
famotidine is not a phosphorus binder. You should ask your vet about using
an aluminium hydroxide based binder.

I'd ask the vet if your boy is anaemic, and treat accordingly if he is. If
possible, you also want his blood pressure checked, and his potassium
levels.

There is info on all these issues at http://www.felinecrf.org

Finally, I'd suggest you join the CRF support list at

http://www.yahoogroups.com/group/Feline-CRF-Support

HTH

Helen
Mavalon - 15 Sep 2003 19:15 GMT
Thanks so much everyone for responding.  I truly appreciate the input.
Kitty has been home for 2.5 days now. Though the vet's prognosis is
bad, he finally starting eating a bit on his own.  We're thrilled to
death.  He seems to be doing much better and we see glimpses of his
old self. He's not eating the prescription food, but small amounts of
Iams wet food.  At this point I figure it's better than nothing at
all.  I'm also supplementing him with prescription food. Helen, the
reason I was force feeding was that he was refusing to eat anything at
all, and I figured if I had to force feed, it's better that he have
the low protein, low phosphorus. He has lost quite a bit of weight,
but now that he''s eating on his own, we're hoping he'll gain some
back.  He was always a strong, solid, muscular cat.  It's
heartbreaking to see him so thin.

We're continuing with fluids, antibiotics, tonic-lax (for
constipation), and famotidine.  I asked the vet about the phosphorus
binder and she wrote a prescription for Amphojel.  We've been giving
him 1 ml with his food.

We've been dealing with a few different vets throughout his crisis, as
they appear to work shifts.  The vet on Saturday, told us it looks
very bad, let him live out his last couple of weeks at home and don't
bother bringing him back for blood tests.  On Sunday, I spoke with the
vet who initially admitted him.  She was a bit more optimistic.  She
encouraged us to continue what we're doing and said that it was very
good that he's starting to eat and that he's holding his food down.
She wants us to bring him back in a couple of weeks for more blood
work and she said she wants to check his blood pressure.  I don't
think she checked for a block or stone as she didn't mention anything
about it.  I will ask her though.  I will not use garlic anymore.  I
had read that onion was bad, but I thought I'd try garlic just the one
time to try to encourage him.  It worked.

He appears to be doing 100% better than he was when we first brought
him home.  He was scratching his post, joined me in the kitchen while
I cooked supper last night, groomed his brother last night, (Couldn't
believe it when I saw it!  Here he is, fighting for his life and he's
grooming his brother!), and though he's still a sick cat, we are
praying that these are signs that he's pulling though.

Phil, he's urinating no problem and always has been.  Perhaps a bit
too much.  I'm going to keep the peritoneal dialysis in mind.  His
recent progress has made me reluctant to do much poking and prodding
with him, and I'm scared that another trip to the vet's will put him
over the edge. If we see any more signs of further deterioration, I
may look at this option.  Any idea what the costs are?  Has anyone
ever had their cat go through this?

I gave him some small chucks of plain chicken breast last night which
he gobbled down.  Is this ok to do this with him?  If anyone has
advice for his diet, I'd love to hear.

We're planning on moving in two weeks and and very concerned about the
effect this will have on him if he's still around.  We bought our
first home and up until this crisis, we were busily packing and very
excited about the move.  However, kitty's illness has dramatically
changed our enthusiasm.  Our first priority is getting this guy better
so that he can enjoy our new home with us.  Does anyone have any
thoughts on the move and how we might make it more tolerable for him?

Will keep everyone posted on kitty's progress, and thanks so much for
the support.
Phil P. - 16 Sep 2003 15:46 GMT
> Thanks so much everyone for responding.  I truly appreciate the input.
>  Kitty has been home for 2.5 days now. Though the vet's prognosis is
[quoted text clipped - 19 lines]
> very bad, let him live out his last couple of weeks at home and don't
> bother bringing him back for blood tests.

Delete that vet... Your cat doesn't need a pessimistic quitter.  Attitudes
like that are often a cover for the lack of expertise.

On Sunday, I spoke with the
> vet who initially admitted him.  She was a bit more optimistic.  She
> encouraged us to continue what we're doing and said that it was very
> good that he's starting to eat and that he's holding his food down.
> She wants us to bring him back in a couple of weeks for more blood
> work and she said she wants to check his blood pressure.

Now that vet is on the ball!  Hypertension is a very serious complication of
CRF and among other things, can lead to blindness. You want a vet who will
fight as hard as you and cat.

I don't
> think she checked for a block or stone as she didn't mention anything
> about it.  I will ask her though.

If he's urinating ok, he's not blocked.

I will not use garlic anymore.  I
> had read that onion was bad, but I thought I'd try garlic just the one
> time to try to encourage him.  It worked.
[quoted text clipped - 5 lines]
> grooming his brother!), and though he's still a sick cat, we are
> praying that these are signs that he's pulling though.

They are.

> Phil, he's urinating no problem and always has been.  Perhaps a bit
> too much.

A bit too much is actually "good" right now and probably largely a result of
the fluid
therapy.  That means diuresis has begun and he's excreting some of the
uremic toxins.
That's probably why he's feeling better.  The build up of uremic toxins make
a cat feel sick and not feel like eating.  As the BUN/Cr come down, his
appetite should improve.

Diuresis can lower BUN/Cr rapidly because it improves GFR.  Just remember
that fluid therapy to promote diuresis should be used only on a short term
basis because it creates an increased workload on the kidneys which can lead
to the progression of CRF.  Long term fluid therapy should only be used to
correct or prevent dehydration.  A lot of people seem to think diuresis can
be used as a simple dialysis -- They're dead wrong.

I'm going to keep the peritoneal dialysis in mind.  His
> recent progress has made me reluctant to do much poking and prodding
> with him, and I'm scared that another trip to the vet's will put him
> over the edge.

Since he's improving, PD probably isn't necessary -- or even a good idea.
PD is good for removing uremic toxins and lowering the BUN when nothing else
works.

If we see any more signs of further deterioration, I
> may look at this option.  Any idea what the costs are?

The cost vary with vets.  The fee can be as low as $200 or as high as $600
or even higher - It all depends on the vet.

Has anyone
> ever had their cat go through this?
>
> I gave him some small chucks of plain chicken breast last night which
> he gobbled down.  Is this ok to do this with him?

Absolutely!  The most important issue is that he eats!  It doesn't matter
how perfectly formulated a renal diet is if the cat won't eat it.  Speak to
your vet about supplementing his energy needs with non-protein calories.
Leave the skin on the chicken breast - its a good source of fat and
non-protein calories.

If anyone has
> advice for his diet, I'd love to hear.
>
[quoted text clipped - 5 lines]
> so that he can enjoy our new home with us.  Does anyone have any
> thoughts on the move and how we might make it more tolerable for him?

I don't know how well your cat reacts or adapts to changes in his
environment - especially drastic ones.  I would delay the move until he's
stabilized - but that's just me.

> Will keep everyone posted on kitty's progress, and thanks so much for
> the support.

Although CRF can occur at almost any age, but since he's only 5 years old,
my gut feeling is acute renal failure which is *reversible*.  I get the
impression that the onset of his symptoms was sudden rather than a gradual
build up to a uremic crisis.

Don't let anyone talk you into doing anything drastic based on numbers
alone - go by the *cat* only.  Many cats make a dramatic comeback after a
uremic crisis - which your cat seems to be doing.  My best advice is go the
distance!

I wish you the very best of luck.

Phil.
Mavalon - 16 Sep 2003 21:15 GMT
> Diuresis can lower BUN/Cr rapidly because it improves GFR.  Just remember
> that fluid therapy to promote diuresis should be used only on a short term
> basis because it creates an increased workload on the kidneys which can lead
> to the progression of CRF.  Long term fluid therapy should only be used to
> correct or prevent dehydration.  A lot of people seem to think diuresis can
> be used as a simple dialysis -- They're dead wrong.

What would be short term?  Days, weeks, months? If he continues to
improve as he has been, when do I know it's ok to take him off?

> I don't know how well your cat reacts or adapts to changes in his
> environment - especially drastic ones.  I would delay the move until he's
> stabilized - but that's just me.

Unfortunately, delaying the move is not an option.  We have to be out
of our condo on the 30th.  I'm unsure whether I should take #1 (yes,
that's his name & we have a #2 as well), back for bloodwork before or
after the move. I want to get an accurate reading and I understand
stress can affect his numbers.

> Although CRF can occur at almost any age, but since he's only 5 years old,
> my gut feeling is acute renal failure which is *reversible*.  I get the
> impression that the onset of his symptoms was sudden rather than a gradual
> build up to a uremic crisis.

Phil, I'm completely with you on this one.  His symptoms came on
extremely sudden and were so high!  About a week before we noticed
symptoms, we brought  a clipping from an outside creeping ground
ivy-type plant and set it in some water in attempts to root it.  #1
has always been a very curious cat, and we have previously caught him
numerous times chomping away on flowers in vases.  He definately got
into the plant we were trying to root, and I strongly suspect this as
the cause.  Of course I told the vet, and she agreed it's possible.  I
swear....I will never, ever, buy or bring another plant or flower
inside my house unless I know for certain that it could not harm my
kitties.

If it is in fact an acute failure, would he completely recover, or
might he still have some kidney damage that we'll have to treat with
diet and the occasional fluid treatment?  I realize I'm ahead of
myself, and we ARE taking it one day at a time, but he seems to be
improving each day.  He's bright eyed,
his coat looks shiny, his dandruff is disappearing, he's continuing to
eat and drink, though I am concerned about his constipation.  He's
been on tonic-lax for almost 2 days now, about 1/2 tsp 3 times a day,
but I don't think he's had a BM yet.  It's hard to say for sure as we
have the two cats.  Any other suggestions?

Phil, your posting brought tears to my eyes.  This is exactly what I
needed to hear!  Thank you so much for your efforts in responding.
Our family has been torn up over this.  For the past week we have been
taking turns, bawling our eyes out over the thought of losing him.  We
just cannot imagine life without him.
Phil P. - 18 Sep 2003 08:01 GMT
> > Diuresis can lower BUN/Cr rapidly because it improves GFR.  Just remember
> > that fluid therapy to promote diuresis should be used only on a short term
[quoted text clipped - 4 lines]
>
> What would be short term?  Days, weeks, months? .

Fluid therapy to supply daily water needs and replace normal ongoing losses
(maintenance) is not the same as fluid diuresis.  Maintenance therapy can
last as long as a few weeks to a few months or until he recovers
sufficiently and voluntarily meets his water needs (from food and drinking).
Fluid therapy to correct dehydration and ongoing (normal) losses should also
reduce the BUN/Cr.because it maintains urine output which facilitates the
normal excretion of uremic toxins

Fluid therapy to promote diuresis (fluid diuresis- FD) should be used only
to manage a uremic crisis.   FD should reduce the BUN/Cr significantly
within 24 hours or within 2 days.  If it doesn't intense diuresis is usually
necessary.

How much and how often is he receiving fluid?  Stop by my site for a fluid
replacement guide:

http://www.maxshouse.com/Calculation_of_24-Hour_Fluid_Requirement_at_Different_L
evels_of_Dehydration.htm


Remember, water intake from food and drinking must be taken into
consideration when you're  calculating his fluid requirement.   One, 5.5 oz
can of cat food that contains 75% moisture contains about 143 ml of water.
Overhydration can cause fluid overload and pulmonary edema.

The fact that he's improved *significantly* so quickly, is a pretty good
indication that the fluid therapy is working and his BUN/Cr are coming down
and also that he could already be in the "recovery phase" of ARF.  The fact
he never became oliguric is also a *very* good sign.

If he continues to
> improve as he has been, when do I know it's ok to take him off?

You won't know without blood tests.  This is why additional blood tests are
so important.  .

You didn't mention urinalysis.  Was one done?  Urine gives a lot of valuable
information about the condition of the kidneys.  The urinalysis should've
been done before beginning fluid therapy because the fluids will influence
the urinary values.  However, urinalysis will still provide some good
information.

> > I don't know how well your cat reacts or adapts to changes in his
> > environment - especially drastic ones.  I would delay the move until he's
[quoted text clipped - 4 lines]
> that's his name & we have a #2 as well), back for bloodwork before or
> after the move.

Before.  He may have recovered by the 30th! ;)

I want to get an accurate reading and I understand
> stress can affect his numbers.

That's true.

> > Although CRF can occur at almost any age, but since he's only 5 years old,
> > my gut feeling is acute renal failure which is *reversible*.  I get the
[quoted text clipped - 3 lines]
> Phil, I'm completely with you on this one.  His symptoms came on
> extremely sudden and were so high!

...and now his symptoms seem to be subsiding almost as rapidly. ;)   These
factors strongly suggest ARF, and that he may be in the recovery phase.

About a week before we noticed
> symptoms, we brought  a clipping from an outside creeping ground
> ivy-type plant and set it in some water in attempts to root it.  #1
> has always been a very curious cat, and we have previously caught him
> numerous times chomping away on flowers in vases.  He definately got
> into the plant we were trying to root, and I strongly suspect this as
> the cause.  Of course I told the vet, and she agreed it's possible.

You might want to bring a sample to your local florist - He might be able to
identify it.  Then stop by my site an see if its on the toxic plants list.
If it isn't on the list, that doesn't mean it isn't toxic.

Could he have gotten at any medication? NSAIDs?  Or antifreeze or cleaning
products?  Do a house search from the cat's point of view just in case the
plant wasn't the culprit.

 I
> swear....I will never, ever, buy or bring another plant or flower
> inside my house unless I know for certain that it could not harm my
> kitties.

I err on the side of caution; I don't have any plants in my house.

> If it is in fact an acute failure, would he completely recover, or
> might he still have some kidney damage that we'll have to treat with
> diet and the occasional fluid treatment?

It could take as long as 3 to 4 weeks of therapy to distinguish reversible
from irreversible renal failure.  Based on your description of his rapid
improvement, my gut feeling is he sustained very little, if any permanent
damage.

I realize I'm ahead of
> myself, and we ARE taking it one day at a time, but he seems to be
> improving each day.  He's bright eyed,
> his coat looks shiny, his dandruff is disappearing, he's continuing to
> eat and drink,

That's  why I think he may already be in the recovery phase of ARF.  I'm not
just saying that to make you feel better - I really mean it!

Just keep a close watch on his mouth and tongue for any lesions or signs  of
inflammation.  Cats' breath normally stink, but be on the lookout for an
ammonia odor.  You don't want him to stop eating because of oral pain caused
by uremic lesions.

though I am concerned about his constipation.  He's
> been on tonic-lax for almost 2 days now, about 1/2 tsp 3 times a day,
> but I don't think he's had a BM yet.  It's hard to say for sure as we
> have the two cats.  Any other suggestions?

You may want to speak to your vet about a plain baby glycerin suppository.
Some baby suppositories come with lubricated applicators preloaded with
plain glycerin.  The applicator looks like a eye dropper with a ball at the
end instead of the slim rubber reservoir.  Very fast and easy to use.

Constipation can be a real problem in cats because it tends to be
self-perpetuating -- regardless of the cause.  The longer the stools remain
in the rectum the drier and harder they become and the more painful they are
to eliminate.  This can lead to *voluntary* fecal retention and eventually
obstipation and megacolon.  So if he's constipated, you want to resolve it
as quickly as possible

> Phil, your posting brought tears to my eyes.  This is exactly what I
> needed to hear!  Thank you so much for your efforts in responding.

Its what I really believe.

> Our family has been torn up over this.  For the past week we have been
> taking turns, bawling our eyes out over the thought of losing him.  We
> just cannot imagine life without him.

If you allow only the optimistic vet to handle his case, my gut feeling
tells me he'll with you for a long time.  I really mean that! ;)

Please keep me posted on his progress.

Keep the faith!.

Phil.
Mavalon - 18 Sep 2003 22:50 GMT
He's currently receiving between 100-120 ml of subq daily depending on
how well he's sitting for us to take it.  We definately get at least
100 ml into him daily.  I'm worried about giving him too much fluid.
Do you think I should reduce his doses anytime soon?  The vets think I
should keep him on 100-120 ml daily at least for the next month.  The
plan is to bring him in for bloodwork in a months time after we move.
I want to get him settled in the new place.  He's peeing lots, and
he's had two bowels movements in the past two days.  They were very
dark brown (almost black) and quite hard.  I hope this will get things
moving again.  I think we'll still give him the tonic-lax until we
know for sure things are moving as they should be.  The vet said the
amphojel might constipate him so I think continuing the tonic-lax
won't hurt. It also contains a bunch of extra vitamins that he could
probably use right now.  He seems to be continually improving.  His
alert times are getting longer and he's even had a few playful
moments.  When we first brought him home from the vet, all's he did
was sleep.  And it didn't look like a comfortable sleep.  He would
curl his paws underneath him and hold his head down.  Now he's
stretching right out and looks alot more comfortable.  It's funny how
you don't really notice the small, seemingly insignificant behaviour
until they stop doing it.  I think he may have even put a little
weight back on.  He doesn't feel as skinny and spiny as he did a few
days ago.  Maybe it's all in my head.

What are the signs of being oliguric, and what is oliguric?  I don't
know what any of this means, but here's the urinalysis that was taken
the day he was admitted (last Tuesday):

PH:        6.0
SP.GRV:    1.020
APPEAR:    Clear
COLOR:     Pale
PROTEIN:   1g/1
GLUCOSE:   Neg
KETONE:    Neg
BLOOD:     trace
BILIRUB:   Neg
UROBIL:    Norm
WCB:       0 -3
RBC:       0 -3
EPITH:     Many
HYAL CAST: Neg
GRAN CAST: Neg
RBC CAST:  Neg
BACTERIA:  Neg
MUCUS:     Neg
CRYSTALS:
AMOUNT:

Here's the comment by the tech:

amorphous debris present
Few transitional epithelium present
Few clumps of epithelium present
T015
HYPERGLYCEMIA - STRESS
RENAL AZOTEMIA AND PROTEINURIA - RATIO?

Do you see anything notable here Phil?

I guess it's always possible that he got into household chemical, but
it's very unlikely.  Everything is kept put away in a cupboard and I'm
pretty sure he can't open the cupboards. Medications? Again, unlikely.
No possible way he got into antifreeze. He's indoor only. I'm still
leaning towards the plant.  We're going to find out what it is.  Once
we find out, I'll let you know just in case it's not on your list so
you can add it.

Again, thanks so much for your attention to our crisis.  You have no
idea how much it means to me.
Phil P. - 19 Sep 2003 19:49 GMT
> He's currently receiving between 100-120 ml of subq daily depending on
> how well he's sitting for us to take it.  We definately get at least
> 100 ml into him daily.  I'm worried about giving him too much fluid.
> Do you think I should reduce his doses anytime soon?

It doesn't seem like too much - but I can't say for sure because I don't
know how much water he's consuming daily from drinking and from food.  A
very rough estimate of a healthy cat's daily water needs is about 1
oz/lb.BW/day  or 60 ml/kg BW/day.

A more accurate "guesstimate" of water needs:(in milliliters) is equal to
the cat's metabolizable energy requirement in kcals.  .IOW, a cat with a
daily energy requirement of 180 kcals has a daily water requirement of about
180 ml (including drinking and water in the food).  Again these are just
*maintenance* estimates for normal healthy cats that are eating normally and
doesn't include water to correct dehydration or to replace excessive ongoing
losses.  Those replacement values are added to the maintenance water needs.

The vets think I
> should keep him on 100-120 ml daily at least for the next month. The
> plan is to bring him in for bloodwork in a months time after we move.

I don't think I'd wait a month for a recheck.

> I want to get him settled in the new place.  He's peeing lots, and
> he's had two bowels movements in the past two days.  They were very
> dark brown (almost black) and quite hard.

You might want to drop off a stool sample with your vet to check for blood.
If these we his first BM in a few days, the stools were  dry and hard
probably because they weren't eliminated right away.  The longer stools
remain in the colon/rectum the drier and harder they become because water is
drawn out.

I hope this will get things
> moving again.  I think we'll still give him the tonic-lax until we
> know for sure things are moving as they should be.  The vet said the
[quoted text clipped - 3 lines]
> alert times are getting longer and he's even had a few playful
> moments.

You're convincing me with every post that he's probably in the recovery
phase of ARF!

When we first brought him home from the vet, all's he did
> was sleep.  And it didn't look like a comfortable sleep.  He would
> curl his paws underneath him and hold his head down.  Now he's
> stretching right out and looks alot more comfortable.  It's funny how
> you don't really notice the small, seemingly insignificant behaviour
> until they stop doing it.

You know something?  You're right!

I think he may have even put a little
> weight back on.  He doesn't feel as skinny and spiny as he did a few
> days ago.  Maybe it's all in my head.

I know you've already had some heavy vet bills, but if you can afford a good
pediatric scale, it would be one of the best investments you can make in
your cats' healthcare program.  Subtle weight gains and losses are difficult
to notice in a cat you see everyday.  Suble losses that aren't obvious to
the eye can be an early warning that might help you catch a disease in the
early stages when they're the most responsive to treatment.  This is the
scale I recommend:  http://tanitascale.com/pro_scales/1583.html

> What are the signs of being oliguric, and what is oliguric?

Producing very small amounts of urine.

I don't
> know what any of this means, but here's the urinalysis that was taken
> the day he was admitted (last Tuesday):
>
> PH:        6.0

> SP.GRV:    1.020

Dilute - but could be a result of fluid therapy.

> APPEAR:    Clear
> COLOR:     Pale

> PROTEIN:   1g/1

..This is consistant with but not limited to exposure to nephrotoxins and
supports your hunch about the plant.

> GLUCOSE:   Neg
> KETONE:    Neg
[quoted text clipped - 17 lines]
> Few transitional epithelium present
> Few clumps of epithelium present

Was the urine sample collected via a catheter?

> T015
> HYPERGLYCEMIA - STRESS
> RENAL AZOTEMIA AND PROTEINURIA - RATIO?
>
> Do you see anything notable here Phil?

Nothing really remarkable.  Although the dilute urine has me a little
worried.  Was this urinalysis done before or after starting fluid therapy?

> I guess it's always possible that he got into household chemical, but
> it's very unlikely.  Everything is kept put away in a cupboard and I'm
[quoted text clipped - 3 lines]
> we find out, I'll let you know just in case it's not on your list so
> you can add it.

I'd really appreciate that - might save other cats.  That list is a
never-ending work in progress!

> Again, thanks so much for your attention to our crisis.  You have no
> idea how much it means to me.

Everything you've said sure sounds like he's in the recovery phase!  I think
he's in the back stretch rapidly heading for the home stretch!

The best advice I can give you is stick with the vet who wants to fight and
keep your cat as far away from "the quitter" as possible!

Keep the faith!

Phil.
Mavalon - 15 Oct 2003 21:02 GMT
Just wanted to post an update.  I got the results of #1's repeat
bloodwork back today.  Here's the important numbers:

BUN: 59.94
Creat: 2.57
Phosph: 3.28

Here's what they were previously:

Sept 10/03 (initial examination)
BUN: 115
Creat: 8.02
Phosph: 7.73

Sept 13/03 (after 3.5 days of IV fluids)
BUN: 133
Creat: 10.48
Phosph: 9.56

I am relieved that his numbers have come down significantly.  The
vet's advice is to reduce his subqs from 100 ml daily to 60-80 every
other day.  She'd also like me to cut back his phosphorus binders to
once a day and continue with the famotidine every other day.  I'll
bring him back for more follow-up bloodwork in 3-4 weeks time.  #1 is
doing amazingly well.  He eats and drinks well, uses the litter box
regularly, is active and wrestling with his brother #2 and pretty much
seems back to normal, though he lost alot of weight while he was sick
and I'd like to see him gain it back.

We are enjoying each day we have with our sweet boys.  We always knew
we loved our cats, but when this crisis happened, it sure hit home
with us and made us appreciate our boys even more.
Phil P. - 17 Oct 2003 05:48 GMT
> Just wanted to post an update.  I got the results of #1's repeat
> bloodwork back today.  Here's the important numbers:
[quoted text clipped - 28 lines]
> we loved our cats, but when this crisis happened, it sure hit home
> with us and made us appreciate our boys even more.

Thanks for the update! I was worried that someone might have talked you into
something drastic.  You sure made my day!

The rapid onset of symptoms and then fairly rapid and significant
improvements are certainly indicators of the recovery phase of acute renal
failure.  The recovery phase can take several weeks to a month or so.  This
is the phase of repair and regeneration of renal tissue and restoration of
renal function.  This is certainly evident by the progressive resolution of
the azotemia and return to normal activity!

I just *love* happy endings!!!

Thanks so much for the update! and please keep me posted.

The very best of luck,

Phil.
Liz - 15 Sep 2003 12:56 GMT
So sorry about your cat. His blood might be very acidic (metabolic
acidosis). Did you vet test total CO2 (TCO)? That´s how you´d know. If
you manage to correct his blood pH, all those numbers will come down.
Did you get him on a kidney diet?
THE BIG GUY - 15 Sep 2003 19:25 GMT
i hope the best....i lost my cat franky due to kidney failure......
 
Sign In
Join
My Latest Posts
My Monitored Threads
My Blog
My Photo Gallery
My Profile
My Homepage

Start New Thread
Enable EMail Alerts
Rate this Thread



©2008 Advenet LLC   Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.