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Yes, my vet used it on my cats when our new foster turned out to have fleas.
Quick and easy. Snip off the tip of the tube. Rub it on the cat's skin
between the shoulder blades. No more fleas.
Best regards,
---Cindy S.

Revolution is one of the most frequently-recommended flea pareparations,
largely because of what you were told.  However, I used it on only one
occasion and would *never* use it again.  First, I used it on Holly.  It
annoyed her, but I discounted that because she really doe not like to have
*any* medication.  Then, I put it on poor Duffy.  As soon as the Frontline
was applied, he jumped straight up in the air and began to run in circles in
full speed.  He was in total panic, and I was also in a panic because Duffy
is blind and I was afraid he would run head-on into something and injure
himself.  He actually did hit the wall or furniture a few times before I
could grab him because he was running at such a high rate of speed that I
couldn't get to him.  It is very unusual for Duffy to become disoriented or
hit something, but he was so stressed-out and frightened that he obviously
didn't know what he was doing.  I took the remaining doses back to the vet
and asked about the reaction.  I was told that his reaction was extremely
rare, but they has had other reports to a much lighter extent.  They
*guessed* that it might have felt extremely cold to the cats and startled
them.

I have not needed to use any flea preparation more than a few times, but I
used Advantage on every other occasion and have never had any problems with
it.  I know my experience is unusual, but it is something you might want to
consider or ask your vet about.

MaryL

5 or 6 years ago my vet recommended Revolution.
I've used the kitten version on kittens with no
problems, and the adult version on all my adult and
senior cats, including one 18 year old.  Several of
the cats go outdoors for brief periods under
supervision, but that's enough exposure that I prefer
the more comprehensive treatment of Revolution.

Gail F.

We live in an area that has heartworms and fleas.  We used to use Advantage
for fleas and Heartgard for heartworms. Advantage is drops that are applied
to between the shoulder blades and Heartgard is a rather large tablet that
they are supposed to eat.  I had to break the Heartgard apart and put it in
their food, but they didn't like it and I had a hard time convincing them to
eat it.  Both are administered once a month.

Heartworm protection is recommended, even for indoor cats because mosquitoes
do come inside.

I was happy to switch them to Revolution because it is applied the same as
Advantage and also protects against heartworms, as well as other parasites.

The cats don't like it about the same as they don't like Advantage.  But,
neither has had a bad reaction except to run away after it is applied.  We
have to sneak up on them because they know when we open the little vial.  I
suspect there are some sort of fumes or odor that tips them off.

Apparently, the heartworm protection is important now, even in areas not
associated with it.  When we were visiting relatives in Washington State, we
saw an article in the local paper that heartworm had been diagnosed for the
first time in the area, and the pets had not been to heartworm infested
areas.  The vet interviewed thought that pets that were rescued because of
Hurricane Katrina brought it with them and local mosquitoes bit those pets
and passed it on to local pets.

Who knows?

Hope this helps.

Annie

I didn't find Revolution very effective against fleas. I'd stick with
Frontline or Advantage.

Phil

Suddenly, without warning, Lynne exclaimed (26-Jan-07 10:26 AM):

I use Revolution (Stronghold in some countries) on Meep, as she has
Duffy's reaction to Frontline and Frontline Plus - completely freaks,
and it's worse each time.

She has a bit of reaction to Revolution too, but it's much less frantic.
 It certainly has DMSO or something similar - as soon as I start
applying it, she starts licking/smacking her lips a bit, like it tastes
bad (and yes, I put it between her shoulders).

Never had any problem, and when she did pick up something from the
garden one spring - I hadn't applied anything to her over the winter -
it killed 'em off in record time.

It *is* rather expensive, and only available by prescription, but I've
been quite happy with it.

jmc