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Cat Forum / Health and Behavior / March 2006

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Question on anemia/kidney disease

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gamin@corecomm.net - 01 Mar 2006 17:55 GMT
I was hoping for some advice. I have a 19 year old tortoise shell cat,
Pumpkin, who was diagnosed with kidney problems last year. Since then,
she has only been eating the Hill's K/D diet and has been doing well.
On a recent blood check, the doctor found she is anemic and her kidney
function was a bit worse. He said there was a drug which provided an
artificial form of erythropoietin to stimulate red blood cell
production - maybe similar to Procrit? Then he found that 1 out of 3
cats are subject to a serious side effect which affects the immune
system and causes even less blood cell production (although he said he
hasn't seen that in his practice in about a dozen uses). But anyway, we
decided to hold off on that now due to the high risk. He prescribed a
blood pressure medication to help her kidney function and she will
continue on K/D.

I was wondering if anyone thought she needed any other treatments right
now, and if there was maybe a holistic treatment to enhance blood cell
production - something that is very safe. He has not recommended fluid
therapy at this point.

Thanks for any information or shared experiences.

Janet Levy
Anna - 01 Mar 2006 18:04 GMT
>now, and if there was maybe a holistic treatment to enhance blood cell
>production - something that is very safe. He has not recommended fluid
>therapy at this point.

http://www.felinecrf.org/
http://www.felinecrf.com/
http://groups.yahoo.com/group/Feline-CRF-Support/

Sorry I do not know the answer to this but have provided some links you may
find useful along with a support group too.

Anna
PawsForThought - 01 Mar 2006 18:13 GMT
> I was wondering if anyone thought she needed any other treatments right
> now,

When I had a CRF cat, she was prescribed fluid therapy, which I gave
her at home, but you said your vet hasn't recommended this for now.

and if there was maybe a holistic treatment to enhance blood cell
> production - something that is very safe.

I would consult with a vet who is well-versed in that area.  Even
though a remedy may be natural, it's not always safer.   If you live in
the U.S., you can find a holistic vet in a state by state listing at
www.altvetmed.org.

Best wishes,
Lauren
Phil P. - 02 Mar 2006 07:16 GMT
> I was hoping for some advice. I have a 19 year old tortoise shell cat,
> Pumpkin, who was diagnosed with kidney problems last year. Since then,
[quoted text clipped - 6 lines]
> system and causes even less blood cell production (although he said he
> hasn't seen that in his practice in about a dozen uses).

I have read this, too, but I've never seen it happen in all the years I've
been trearing CRF cats with r-HuEPO. Even the cats that required long-term
Epo therapy didn't develop anti-epo antibodies.

The way I see it- the benefits of EPO outweight the risks since without EPO
many cats would have probably needed transfusions, anyway.  Even if the cat
does
develop antibodies- its reversible- and resolves by simply stopping EPO
therapy.  The cat's PCV just needs to be monitored closely because if the
cat does develop antibodies they can neutralize the cat's own EPO and cause
life-threatening anemia.  But again. I've never seen it happen in >10 years
that I've been using EPO in cats.

If you opt for EPO therapy, the cat will need an iron supplement because
forced RBC production really puts a strain on the cat's body stores of iron.

A feline EPO has been developed- but I don't know if its available
commercially yet.

But anyway, we
> decided to hold off on that now due to the high risk. He prescribed a
> blood pressure medication to help her kidney function and she will
[quoted text clipped - 4 lines]
> production - something that is very safe. He has not recommended fluid
> therapy at this point.

You might want to speak to your vet about an iron supplement.  A lot of cats
with CRF have anemia caused by iron deficiency.  Sometimes the anemia can be
reversed with a simple iron supplement. Serum iron levels aren't an accurate
marker of the cat's total body stores of iron.  So, even though the cat may
have normal iron levels, she might still need an iron supplement.  The only
problem with iron supplements is that they can cause diarrhea in cats, but
you can get around this by splitting the dose into a few smaller doses and
giving them a few hours apart.

I don't recommend anabolic steriods (stanozolol)- they're hepatoxic and
aren't very effective at stimulating red blood production.  IOW, the risks
outweigh the benefits.

Best of luck,

Phil
 
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