"Commonwealth of Australia Gazette. APVMA No. 10 7 October 2003.
Agricultural and Veterinary Chemicals Code Act 1994.
NOTICE
Reconsideration of Approvals and Registrations
Related to Fipronil

"The APVMA, in accordance with Part 2, Division 4, of the Agve t Codes, intends
to reconsider all
approvals of the active constituent fipronil, registrations of all products
containing fipronil and
the approvals of all associated product labels. The active constituent
approvals to be
reconsidered are listed in Table 1. The product registrations and associated
label approvals to be
reconsidered are listed in Table 2.
Fipronil is a broad spectrum insecticide that belongs to a relatively new class
of pesticides. Its
mechanism of action is interference with the insect central nervous system.
Fipronil is used in
veterinary chemical products to control fleas and ticks on cats and dogs and in
agricultural
chemical products to control a range of insect pests in agricultural crops. It
is also included in a
number of household products such as cockroach baits and gels and in ant bait
stations.
The APVMA has recorded adverse experience reports that are suspected to be
attributed to
products containing fipronil, primarily in veterinary chemical products.
In view of these reports the APVMA will consider whether fipronil and products
containing
fipronil in the context of both agricultural and veterinary uses:
·  may be an undue hazard to the safety of people exposed to it during its
handling;
·  may have an effect that is harmful to human beings;
·  may have an unintended effect that is harmful to animals; and whether
·  product labels contain adequate instructions with regard to the safe
handling of the
product or other warning and precautionary instructions.
The APVMA will review the following matters relevant to active constituent
approvals, product
registrations and label approvals for fipronil:
·  toxicity of fipronil primarily in relation to dermal irritation and the
induction of skin
sensitisations;
·  toxicity of photodegradation products of fipronil particularly in relation
to neurotoxicity
and dermal absorption;
·  toxicological effects associated with products containing fipronil including
the potential to
form toxic photodegradation products;
·  occupational health and safety issues including the risk to workers mixing,
loading and
applying products containing fipronil or users using products containing
fipronil; risk to
workers on re-entry to treated areas or humans handling animals after they have
been
treated;
·  animal safety; and
·  adequacy of label instructions including suitability of personal protective
equipment,
specified re-entry intervals and other warnings or precautionary instructions."

To read more:  http://www.apvma.gov.au/gazette/gazette0310p59_v2.pdf

Lauren
________
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