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Harry update #3: still positive news

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Dan M - 23 Jun 2005 16:59 GMT
Just got off the phone with Nancy, who just got off the phone with the
vet. Harri is still breathing easily, and the fluid has not reached a
danger level again yet.

I didn't hear a definitive answer as to the makeup of the fluid that was
on Harri's chest - I didn't tell Nancy that we definitely wanted to know
these things. I'll find out late today.

The vet said that Harri's coagulation rate is very poor. This leads him
to believe that Harri got into rat poisin. We have none here at the
house, so it would have have to have happened while whe was on the road
with me. I was really careful about Harri not even sniffing around
powders or crystals or anything of that sort, but I wonder if any of the
bugs or lizards she ate might have been exposed to warfarin?

Anyhow, the vet is administering vitamin K and drugs to help restore he
coagulation function. If this proves to be the case, then Nancy and I
will have to administer vitamin K to Harri once she gets home. We can
deal with that! Harri will be with the specialist for another night, but
I'm even more hopeful now.

Dan
Adrian - 23 Jun 2005 17:07 GMT
> Just got off the phone with Nancy, who just got off the phone with the
> vet. Harri is still breathing easily, and the fluid has not reached a
[quoted text clipped - 19 lines]
>
> Dan

My two will keep purring until Harri is home and well.
MaryL - 23 Jun 2005 17:25 GMT
> The vet said that Harri's coagulation rate is very poor. This leads him to
> believe that Harri got into rat poisin. We have none here at the house, so
[quoted text clipped - 4 lines]
>
> Dan

Dan,

I know you said that you don't have any rat poison around the house.
However, have you seen any mice?  If so, it's possible Harri caught a mouse
that had already ingested a slower-acting poison (from the neighbors or
elsewhere).

It's great to hear that Harri has continued to improve.

MaryL
Dan M - 23 Jun 2005 18:39 GMT
> I know you said that you don't have any rat poison around the house.
> However, have you seen any mice?  If so, it's possible Harri caught a mouse
[quoted text clipped - 4 lines]
>
> MaryL

I hadn't thought of that - I have seen a couple of mice in the two years
we've been here so that's a possibility.
Magic Mood Jeep© - 23 Jun 2005 17:28 GMT
> Just got off the phone with Nancy, who just got off the phone with the
> vet. Harri is still breathing easily, and the fluid has not reached a
[quoted text clipped - 18 lines]
>
> Dan

Good news!

I just paypal'd some funds to Victor to help with Harri (or any other cat
that needs it).  I know I lamented about the lack of funds this late in the
month, but I just had a item sell on eBay for more than I thought it would.
Not much more, but a bit.

Signature

The ONE and ONLY
lefthanded-pathetic-paranoid-psychotic-sarcastic-wiseass-ditzy former-blonde
in Bloomington! (And proud of it, too)©
email me at nalee1964 (at) insightbb (dot) com
http://community.webshots.com/user/mgcmdjeep

wafflycat - 23 Jun 2005 17:28 GMT
Continued good vibes for Harri

helen s
Mary - 23 Jun 2005 17:34 GMT
> Just got off the phone with Nancy, who just got off the phone with the
> vet. Harri is still breathing easily, and the fluid has not reached a
> danger level again yet.

Good!

> I didn't hear a definitive answer as to the makeup of the fluid that was
> on Harri's chest - I didn't tell Nancy that we definitely wanted to know
> these things. I'll find out late today.
>
> The vet said that Harri's coagulation rate is very poor. This leads him
> to believe that Harri got into rat poisin.

Oh no.

>We have none here at the
> house, so it would have have to have happened while whe was on the road
> with me. I was really careful about Harri not even sniffing around
> powders or crystals or anything of that sort, but I wonder if any of the
> bugs or lizards she ate might have been exposed to warfarin?

It certainly seems possible. It's dangerous out there.

> Anyhow, the vet is administering vitamin K and drugs to help restore he
> coagulation function. If this proves to be the case, then Nancy and I
> will have to administer vitamin K to Harri once she gets home. We can
> deal with that! Harri will be with the specialist for another night, but
> I'm even more hopeful now.

I will keep you in my prayers, Dan, and Harri and Nancy too.
Pat - 23 Jun 2005 18:05 GMT
Hopeful news.... I thought it had been a while since you took her on any
trip where she could have been exposed to poison? Also curious how come you
call her Harry sometimes and Harri other times? Still sending our best
recovery purrs.... Please keep us posted.
Dan M - 23 Jun 2005 18:36 GMT
> Hopeful news.... I thought it had been a while since you took her on any
> trip where she could have been exposed to poison? Also curious how come you
> call her Harry sometimes and Harri other times? Still sending our best
> recovery purrs.... Please keep us posted.

About the name - I only call her Harry when I'm REALLY tired and
confused :) I kick myself when I do that.

The last time Harri was on the truck with me was a couple of months ago,
so if that is indeed the case then it has been working on her for a long
time. I did do a thorough walkthrough of the back yard this morning just
to be sure, and am going to do so again a little alter today. I also did
a thorough search of our cabinets and drawers and verified that we do
not have any such chemicals anywhere in the house.
Karen - 23 Jun 2005 18:39 GMT
> Hopeful news.... I thought it had been a while since you took her on any
> trip where she could have been exposed to poison? Also curious how come you
> call her Harry sometimes and Harri other times? Still sending our best
> recovery purrs.... Please keep us posted.

Indeed, I wonder if you shouldn't do a thorough search of your backyard and
make sure no one mean threw something over the fence. It's not unheard of.
It would be worth a thorough examination of the yard anyway.
Dan M - 23 Jun 2005 18:49 GMT
> Indeed, I wonder if you shouldn't do a thorough search of your backyard and
> make sure no one mean threw something over the fence. It's not unheard of.
> It would be worth a thorough examination of the yard anyway.

Done! As soon as I got off the phone with Nancy I was out in the back
yard doing a really thorough inspection. And I plan to so again in an
hour or two when the sun angle has changed a bit. And I think it helps
that our sprinkler system runs for 30 minutes in the wee hours of every
weekday. I think that would help to dissipate any such poisons that
anyone might have placed in the yard.

I sincerly hope that nobody has deliberately tried to poison my babies.
I have the potential for some really bad temper fits, but keep it
tightly in check when I'm around people I care about. If someone tried
to deliberately hurt my babies I would pretty much have to hurt them badly.
MaryL - 23 Jun 2005 19:39 GMT
> I have the potential for some really bad temper fits, but keep it tightly
> in check when I'm around people I care about. If someone tried to
> deliberately hurt my babies I would pretty much have to hurt them badly.

No!!  Don't do that (and I hope you were just "blowing off steam" here).  If
you did injure someone, you could immediately be charged with a criminal
offense -- and how would that leave Nancy and your furbabies?  If you did
find evidence of anyone trying to hurt your babies, *call the police*
instead of trying to take care of it yourself.

MaryL
Howard C. Berkowitz - 23 Jun 2005 18:18 GMT
> Just got off the phone with Nancy, who just got off the phone with the
> vet. Harri is still breathing easily, and the fluid has not reached a
[quoted text clipped - 10 lines]
> powders or crystals or anything of that sort, but I wonder if any of the
> bugs or lizards she ate might have been exposed to warfarin?

That's a fascinating theory that could be right on. There's no
particular reason for coagulation problems if it's chylothorax.
Depending on the specific coagulation profile -- you'd want at least
prothrombin and partial thromboplastin times, the more it matches
warfarin, the better.  I have to go out to a medical appointment very
shortly, but, if you like, I'll pull references and find the specific
diagnostic criteria for warfarin.  I _think_ there's a chapter in the
Handbook of Commercial Toxicology.

I'm doing this partially from memory, but warfarin (also known as
Coumadin) was originally found in some contaminate cattle food. The name
is actually a partial acronym for Wisconsin Agricultural Research
Foundation, whose veterinarians diagnosed the anticoagulant property in
cattle, and then realized they actually might have a useful drug -- and
were right.

This is awfully off the wall, but I wonder if the conditions that
produced warfarin in nature could have occurred in some decomposing
grass she decided to eat.

> Anyhow, the vet is administering vitamin K and drugs to help restore he
> coagulation function. If this proves to be the case, then Nancy and I
[quoted text clipped - 3 lines]
>
> Dan
Dan M - 23 Jun 2005 18:55 GMT
> This is awfully off the wall, but I wonder if the conditions that
> produced warfarin in nature could have occurred in some decomposing
> grass she decided to eat.

Hmmm... that's an interesting possibility. I'll talk to the vet about
it.  I'll be sure to ask also about the prothrombin and partial
thromboplastin times. Thank you so much for the technical info, Howard!
Howard C. Berkowitz - 23 Jun 2005 22:30 GMT
While it's written for veterinarians, there is a very good guide on
anticoagulant poisoning in cats and dogs at
http://www.liphatech.com/vetguide.html.  In particular, it deals with
the wide range of synthetic alternatives to warfarin as a rodenticide.  
Beyond the basic coagulation tests
  prothrombin time
  partial thromboplatin time
  platelet count

it identifies some specialized tests that specifically identify
anticoagulant rodenticides, although the tests are available only from
specialized laboratories -- I'd imagine UC Davis certainly can do it.

I forgot to mention is that a good lab reports, with the prothrombin
time, an Internationalized Normal Ratio (INR).  This corrects for
variations in the particular batch of chemicals used for the actual
test. On deliberate warfarin therapy in humans, the INR should be
between 2 and 3, as close to 2.5 as possible. If it goes above 3, the
dose needs to be reduced.  I did find one article about warfarin therapy
in cats that allows the INR to reach 4.  Certainly, above 4 is
suggestive of poisoning.

Another informative test might be creatine phosphokinase (CK or CPK).  
Muscle cells are rich in this enzyme.  There is a specific subfraction
(CK-MB) that shows damage to heart muscle. If the total CK is high but
the CK-MB is normal, that would be very suggestive that she suffered
trauma.
glsummer@neptunelink.com - 23 Jun 2005 18:20 GMT
>Just got off the phone with Nancy, who just got off the phone with the
>vet. Harri is still breathing easily, and the fluid has not reached a
[quoted text clipped - 18 lines]
>
>Dan

{{{{{Dan}}}}} I am so glad to hear this.  I worried all last night
about Harri, and sent out some furious prayers to Bast.  Will continue
those prayers.  We need a miracle right now, and I think Harri just
*has* to be it!

Ginger-lyn

Home Pages:
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 http://freepages.genealogy.rootsweb.com/~summer/index.htm (genealogy)
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Melissa Houle - 23 Jun 2005 18:26 GMT
> Anyhow, the vet is administering vitamin K and drugs to help restore he
> coagulation function. If this proves to be the case, then Nancy and I
[quoted text clipped - 3 lines]
>
> Dan

I'm hopeful with you.  Harri is such a dear, adventuresome little cat--she
simply has to pull through! The signs sound good so far, though.  My Three
are still on High Purr Alert (Code Orange.)

Melissa
Karen - 23 Jun 2005 18:33 GMT
> Just got off the phone with Nancy, who just got off the phone with the
> vet. Harri is still breathing easily, and the fluid has not reached a
[quoted text clipped - 18 lines]
>
> Dan

That is the rotten thing about pesticides, they can affect animals that eat
affected bugs. If the K works then she can probably work it out of her
system and THAT is better news than if it was some condition that was
dorment in her system. I've just been so worried about her. Keeping up
purrs.
W. Leong - 23 Jun 2005 18:42 GMT
That's good news.
I am always worried about stuff bug sprays in my home.
When I am not home, I confine Rusty in his
room with only his ltter box and food, and some old newspapers.
Other times I keep an eagle eye on him. If I can't see him, I go in
search of him.
I won't even walk on grass for fear of tracking some harmful
pesticide home.
Call me paranoid.

Winnie

> Just got off the phone with Nancy, who just got off the phone with the
> vet. Harri is still breathing easily, and the fluid has not reached a
[quoted text clipped - 18 lines]
>
> Dan
Victor M - 23 Jun 2005 18:50 GMT
> deal with that! Harri will be with the specialist for another night, but
> I'm even more hopeful now.

These are excellent news! We'll keep purring for Harri and for you and
Nancy. This morning when Basho and I were having a love-fest, I told
him to focus his purrs on a brave orange cat named Harri. He looked at
me in the eyes and closed his. :)  I think that meant "you got it
daddy!".

Victor
Steve Touchstone - 23 Jun 2005 20:05 GMT
>Just got off the phone with Nancy, who just got off the phone with the
>vet. Harri is still breathing easily, and the fluid has not reached a
>danger level again yet.
<snip>
>I didn't hear a definitive answer as to the makeup of the fluid that was
>on Harri's chest - I didn't tell Nancy that we definitely wanted to know
>these things. I'll find out late today.

Sounds very hopeful to me, and continuing purrs that she improves
quickly. Hope the vit K does the trick. As to the warfarin, I suppose
something like that could happen pretty much anywhere, maybe even
second hand by eating/chewing on seomthing already dead.

Anyway, the important news is that she seems to be responding to the
treatment, not relapsing.
Signature

Steve Touchstone,
faithful servant of Sammy, Little Bit and the Evil Spot
with loving memories of Rocky (RB)

stouchst@JUNKsirinet.net [remove Junk for email]
Home Page: http://www.sirinet.net/~stouchst/index.html
Cat Pix: http://www.sirinet.net/~stouchst/animals.html

CatNipped - 23 Jun 2005 20:15 GMT
> Just got off the phone with Nancy, who just got off the phone with the
> vet. Harri is still breathing easily, and the fluid has not reached a
[quoted text clipped - 18 lines]
>
> Dan

Well, as bad as that sounds, if it's rat poison then that's actually good
news since it's something they can treat and then she'll be well again
instead of this being an ongoing problem for her.  Tons of purrs still
heading your way for little Harri!

Hugs,

CatNipped
Pamela  Shirk - 23 Jun 2005 23:23 GMT
> The vet said that Harri's coagulation rate is very poor. This leads him to
> believe that Harri got into rat poisin. We have none here at the house, so
> it would have have to have happened while whe was on the road with me. I
> was really careful about Harri not even sniffing around powders or
> crystals or anything of that sort, but I wonder if any of the bugs or
> lizards she ate might have been exposed to warfarin?

OMG warfarin.  That is some seriously nasty stuff.  Dan, I'm so sorry about
little Harri.  I'll ask the owners to continue to purr for her to recover
fully and pray for her.  She's such a sweet and gallant little girl.

Pam S. who's asking the owners to Purr for Dan and Nancy as well
SuzQ - 23 Jun 2005 23:24 GMT
Sounds like there's reason to hope. I'm glad and will keep Spicey on
purrpatrol.
Suz&Spicey
 
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