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Betty's oncology visit

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Takayuki - 02 Sep 2005 02:21 GMT
Last night, I must have been in the bargaining phase of mourning,
because I made a plea to whoever might be listening, if anyone was
listening...

I asked that Betty's life be spared.  In return, I offer my own life.
A life for a life is fair, isn't it?  It's not that I don't love my
life.  I want to see the sun rise, and I want to have children and
watch them grow.  But I'll never see a sunrise that is as pretty as
Betty, and my purely hypothetical babies don't have priority over my
current furry baby.  So her life is more important than mine.  Kill me
in my sleep, I pleaded.

The next morning, I woke up.  My prayers had not been answered.  And
who would there be to bother to fulfill such a wish anyway?  I felt
silly to have even asked.

So today, Betty saw the oncologist.  He examined her and told me about
the nature of the cancer that Betty had.  I was impressed by the
professionalism and knowledge of this oncologist.

But what he told me was pretty much similar to what I've been told all
along, just in greater detail.  Firstly, Betty's cancer is inoperable,
he said.  It has penetrated too much into the jaw.  A clean excision
would be a radical operation that would remove most of the jaw.  Cats
invariably do not adapt to this, he said, and stop eating, although
this option works fairly well on dogs.

Second, this type of tumor is fairly resistant to radiation, and very
resistant to chemotherapy.  But with radiation treatment, Betty could
be expected to live 6 to 8 months.  However, some patients respond
better to these treatments than others

Thirdly, a certain human anti-inflammatory drug is known to slow this
type of cancer in some cases.  Betty can be given a prescription
through an out-of-state pharmacy that does custom reformulations.

So then he asked, what did I want to do?  The oncology center's custom
is to describe the treatments possible, and give pet owners carte
blanche to try anything, or nothing.

I digested all this new information.  I thought about it.  What did I
want for Betty?  Finally, I answered - I don't know whether the answer
came from the mind or front the heart, but I answered.   I said that I
wanted to treat this as aggressively as is logical to do medically,
and continue to escalate until I say stop.

He understood.  So Betty will be starting on the anti-inflammatory
drug, and going through a course of radiation, one treatment weekly
for three weeks, after which the results will be observed, and we'll
decide what to do next.  More radiation?  Chemotherapy, even though
it's a long shot?

The oncologist emphasized that he does not believe this cancer can be
cured.  But maybe its effects can be delayed.  She's going in for her
first treatment on Wednesday.
Jeanne Hedge - 02 Sep 2005 02:25 GMT
{{{{{Tak & Betty}}}}}

Jeanne Hedge, as directed by Natasha

============
http://www.jhedge.com
SuzQ - 03 Sep 2005 00:12 GMT
Tak, I'm so sorry. Remember though Drs tend to be pessimists. Treat Betty
until she tells you to stop. Purrs and prayers from your neighbors.
Suz&Spicey
Karen - 02 Sep 2005 02:40 GMT
Oh Tak, there are no words. I can only wish you luck and pray for the
success that you get some more time with Betty. I am so sorry.
((((((((((HUGS))))))))))
Jo Firey - 02 Sep 2005 02:44 GMT
Sending purrs and prayers as you and Betty deal with what you must.  I hope
you are able to have some more quality time together.

Jo
> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.
EvelynVogtGamble(Divamanque) - 02 Sep 2005 02:45 GMT
> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.

Well, everyone has to make such decisions for themselves,
but are you really sure?  If it were you receiving such
radical treatment, would you really WANT it?  (Personally, I
cannot imagine doing such a thing - I'd rather make my peace
with everyone and bow out with an overdose of something -
so of course I make the same decision for my pets, given
such a bleak prognosis.)  However, we're all different, and
for some of us the mere fact of "life" is more important
than the quality of that life.  Purrs and prayers for you
and Betty, whatever you ultimately do.
badwilson - 02 Sep 2005 04:37 GMT
>> Last night, I must have been in the bargaining phase of mourning,
>> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 21 lines]
>> clean excision would be a radical operation that would remove most
>> of the jaw.  Cats invariably do not adapt to this, he said, and
stop
>> eating, although this option works fairly well on dogs.
>>
[quoted text clipped - 15 lines]
>> answer came from the mind or front the heart, but I answered.   I
>> said that I wanted to treat this as aggressively as is logical to
do
>> medically, and continue to escalate until I say stop.
>>
[quoted text clipped - 18 lines]
> than the quality of that life.  Purrs and prayers for you
> and Betty, whatever you ultimately do.

It's not like 3 treatments of radiation, 1 week apart and taking some
anti-inflammatory drugs would be some kind of horrible treatment that
would ruin her quality of life!  Sheesh!  And she seems not to be in
any kind of pain now, so why not try the treatment first to see if it
will help?
--
Britta
"There is no snooze button on a cat who wants breakfast." -- Unknown
Check out pictures of Vino at:
http://photos.yahoo.com/badwilson click on the Vino album
Takayuki - 02 Sep 2005 04:45 GMT
>Well, everyone has to make such decisions for themselves,
>but are you really sure?  If it were you receiving such
[quoted text clipped - 3 lines]
>so of course I make the same decision for my pets, given
>such a bleak prognosis.)

I'm not sure if it's what Betty wants, but it's what I ended up
wanting to do.  The only difficulty I have applying the Golden Rule,
which is otherwise a wonderful rule, is that we're sometimes different
in what we want done unto us.

For as long as I've had Betty, I've wondered and wondered what she
wants.  Does she want to go out on walks?  Does she want a kitty
companion?  Does she want a new tree?  And in studying her, I've come
to the tentative conclusion that Betty is an creature who is
inherently happy and full of wonder.  So I made one of my
responsibilities maintaining a stable environment that does not
interfere with that happiness and wonder.  The cancer thing is making
this task a bit hard right now.

>  However, we're all different, and
>for some of us the mere fact of "life" is more important
>than the quality of that life.  Purrs and prayers for you
>and Betty, whatever you ultimately do.

Thank you, and I agree with you.  There are such tough choices, we
should look at this situation critically.  The currently scheduled
course of treatments should not affect Betty's quality of life too
much.  The drugs are just anti-inflammatories.  The radiation
treatment is localized to the jaw, and is done under gas anesthesia,
which I think should make it quick, like going to the dentist.  Chemo
doesn't sound too bad either, although that probably depends a lot of
what chemo drug is used.

Basically, I'm making a gamble by putting Betty through a spectrum of
treatments.  I want to see whether she ends up responding well to any
of these techniques.  If the side effects are bad, or she isn't
improving, or the cancer spreads too far, I'll stop.  Either way, it's
likely the cancer will catch up with her, and she'll eventually
succumb to respiratory or other complications.
Karen - 02 Sep 2005 05:13 GMT
>> Well, everyone has to make such decisions for themselves,
>> but are you really sure?  If it were you receiving such
[quoted text clipped - 17 lines]
> interfere with that happiness and wonder.  The cancer thing is making
> this task a bit hard right now.

Tak, I wish you would write a book about you and Betty. You just have such
an amazing perspective and a great ability to express it.

>> However, we're all different, and
>> for some of us the mere fact of "life" is more important
[quoted text clipped - 16 lines]
> likely the cancer will catch up with her, and she'll eventually
> succumb to respiratory or other complications.

As will we all. It's just so hard to think of you and Betty being in that
postition.
Takayuki - 03 Sep 2005 03:50 GMT
>Tak, I wish you would write a book about you and Betty. You just have such
>an amazing perspective and a great ability to express it.

I could do that, except the only people who would read it would be
like you and my mom. :)

Betty is working to cheer me up right now.  She's pawing me.  She also
licked me, which she never does!  She used just her little tongue tip,
and it tickled.
Helen Wheels - 02 Sep 2005 06:01 GMT
<snip>
> Basically, I'm making a gamble by putting Betty through a spectrum of
> treatments.  I want to see whether she ends up responding well to any
> of these techniques.  If the side effects are bad, or she isn't
> improving, or the cancer spreads too far, I'll stop.  Either way, it's
> likely the cancer will catch up with her, and she'll eventually
> succumb to respiratory or other complications.

I think Betty will let you know very clearly if she wants you to stop
the treatments. You seem to be very attuned to her needs.
Howard C. Berkowitz - 02 Sep 2005 04:59 GMT
> Well, everyone has to make such decisions for themselves,
> but are you really sure?  If it were you receiving such
> radical treatment, would you really WANT it?  

"Such radical treatment"?  How do you define "radical"?  
Anti-inflammatory drugs?  Controlled radiation?

How much do you actually know about oncology, such that you blast the
decisions of someone in a very rough place?

(Personally, I
> cannot imagine doing such a thing - I'd rather make my peace
> with everyone and bow out with an overdose of something -
> so of course I make the same decision for my pets, given
> such a bleak prognosis.)  

You don't indicate, by calling rather routine treatment "radical", that
you understand what it is, or aren't projecting your own fears on it.  

?However, we're all different, and
> for some of us the mere fact of "life" is more important
> than the quality of that life.  

Translation: you have a fixation on quality of life, and you fixate on
other than euthanasia for cancere as poor quality. I suggest you learn a
bit more about oncology.

>Purrs and prayers for you
> and Betty, whatever you ultimately do.

I suppose this formality absolves you from second-guessing Takayuki?
Yes, I am angry with you.
Wayne Mitchell - 02 Sep 2005 16:04 GMT
>?However, we're all different, and
>> for some of us the mere fact of "life" is more important
[quoted text clipped - 9 lines]
>I suppose this formality absolves you from second-guessing Takayuki?
>Yes, I am angry with you.

In fairness, Howard, I don't think Evelyn's message was
particularly second-guessing or accusatory in tone.  She was
just expressing her own viewpoint, and presented it as a
*question* for Tak.

If I use the test she proposes -- what would I want done to *me*
-- I would agree with her.  I've long decided that I have no
interest in difficult procedures to extend my life.  For humans,
who can envision the future, the choice of euthanasia at an
early stage can be the best one.  (Would that it were as readily
available for us as for our pets.)

Cat's, however, are different.  They don't anticipate, so that
isn't part of the equation for them.  They have no fear of pain
or suffering in the future, and no fear of becoming useless and
dependent.  Their quality of life doesn't suffer much until
their physical condition prevents them from being themselves --
from looking out on their environment with interest or getting
comfortable enough to rest.
 
Tak, I like the way you went about making this very difficult
decision, looking at Betty as an individual.  You'll probably
second guess yourself, at times, but if Betty isn't too
terrified of the treatments themselves, then why not take the
gamble that her time of being "happy and full of wonder" can be
prolonged?  She just wants to be Betty.  You'll know when that's
not possible any more (and because you're human, you'll
anticipate that time and suffer far longer than she will.)

For your suffering, my sympathy; for your courage and
competence, my respect.

Signature

Wayne M
(indulged by Will and Heidi)

Howard C. Berkowitz - 02 Sep 2005 20:11 GMT
> >?However, we're all different, and
> >> for some of us the mere fact of "life" is more important
[quoted text clipped - 14 lines]
> just expressing her own viewpoint, and presented it as a
> *question* for Tak.

I'm sorry, I have to disagree. Tak clearly had made a decision.

Now, if Evelyn had described, with knowledge, the potential effects of
radiation, that would be useful information.

The use of NSAIDs demonstrated to have a chance of causing tumor
regression is hardly radical, and, far beyond the chances of regression,
will control pain.  I offered a basic suggestion about them, and I offer
to do a literature search on whether COX-2 inhibitors are superior to
nonselective cyclooxygenase inhibitors.

> If I use the test she proposes -- what would I want done to *me*
> -- I would agree with her.  I've long decided that I have no
> interest in difficult procedures to extend my life.

I don't disagree with this, and, indeed, my own advanced directives are
very, very specific about the conditions under which I want nothing but
comfort measures, the exception conditions such as I am a viable organ
donor candidate, and the perfectly legal things that are effectively
euthanasia.  As an example of the latter, I specify that if I have a
confirmed organic dementia, and am unable to discuss choices, with no
reasonable medical chance of recovery functions, I absolutely forbid the
use of antibiotics, although authorize specific comfort measures. That
effectively means I am likely to die, comfortably, of pneumonia.

But I keep returning to the point that Evelyn was assuming everything
was radical, when not everything being proposed was radical. Potentially
with some other drugs to strengthen bone and further reduce
inflammation, I know of humans with bone metastases that have had a
meaningful extension of life of decent quality.

> For humans,
> who can envision the future, the choice of euthanasia at an
[quoted text clipped - 8 lines]
> from looking out on their environment with interest or getting
> comfortable enough to rest.

Exactly. The NSAID therapy is a comfort measure that may induce
regression.  Radiation can be used in different ways, and one technique,
particularly appropriate to bone cancer, is "palliative" rather than
curative: it is a lower level, with lesser side effects, that helps
control the physical size of tumors. The tumor doesn't disappear, but
doesn't spread such that it presses on nerves.

>  
> Tak, I like the way you went about making this very difficult
[quoted text clipped - 3 lines]
> gamble that her time of being "happy and full of wonder" can be
> prolonged?  

I agree completely with that, and, speaking from knowledge of the
treatments mentioned, do not find them especially radical.  If they do
not reduce pain, then, indeed, the difficult choice of euthanasia may be
appropriate. I've dealt with humans at that stage, where euthanasia was
not an option, but the rational and humane thing was to induce
barbiturate coma, essentially a state of anesthesia from which the
patient will not wake up.

Now, what I'm about to say is extremely rare, but there are cases where
induced coma can, in rare circumstances, help the body heal. There is
some neurochemical and immunologic reasoning to this, although it's
something you can't count upon.

My objection is that if someone wants to advise against "radical" care,
they have enough knowledge of the proposed treatments to explain why
they might be inappropriate.

Hopefully as a bit of tension release, if a bone-strengthening drug is
prescribed, I'd sort of like it to be calcitonin.  Most forms of
calcitonin are prepared from salmon, so perhaps it would be a cat treat.

> She just wants to be Betty.  You'll know when that's
> not possible any more (and because you're human, you'll
> anticipate that time and suffer far longer than she will.)
>
> For your suffering, my sympathy; for your courage and
> competence, my respect.
Takayuki - 03 Sep 2005 04:19 GMT
>The use of NSAIDs demonstrated to have a chance of causing tumor
>regression is hardly radical, and, far beyond the chances of regression,
>will control pain.  I offered a basic suggestion about them, and I offer
>to do a literature search on whether COX-2 inhibitors are superior to
>nonselective cyclooxygenase inhibitors.

Just incidentally, I talked with the pharmacist today, and she told me
that the anti-inflammatory that was prescribed is called Peroxicam, I
think.  It's to be administered 1 mg daily for up to four months.
Howard C. Berkowitz - 03 Sep 2005 04:49 GMT
> >The use of NSAIDs demonstrated to have a chance of causing tumor
> >regression is hardly radical, and, far beyond the chances of regression,
[quoted text clipped - 5 lines]
> that the anti-inflammatory that was prescribed is called Peroxicam, I
> think.  It's to be administered 1 mg daily for up to four months.

Piroxicam is a respected nonselective of a different family.  It's a
prescription drug for humans, but not especially toxic.
SuzQ - 03 Sep 2005 00:21 GMT
Tak, I like the way you went about making this very difficult
decision, looking at Betty as an individual.  You'll probably
second guess yourself, at times, but if Betty isn't too
terrified of the treatments themselves, then why not take the
gamble that her time of being "happy and full of wonder" can be
prolonged?  She just wants to be Betty.  You'll know when that's
not possible any more (and because you're human, you'll
anticipate that time and suffer far longer than she will.)

For your suffering, my sympathy; for your courage and
competence, my respect.

Signature

Wayne M
(indulged by Will and Heidi)

========================================
What he said. Eloquently put Wayne.
Suz

Takayuki - 03 Sep 2005 04:15 GMT
>Tak, I like the way you went about making this very difficult
>decision, looking at Betty as an individual.  You'll probably
[quoted text clipped - 4 lines]
>not possible any more (and because you're human, you'll
>anticipate that time and suffer far longer than she will.)

You have a very logical and measured way of looking at things.  I
don't think I'm quite that reasoned in my thinking, but I think that
in similar circumstances, we'd make similar decisions.
Christina Websell - 02 Sep 2005 19:22 GMT
>> Well, everyone has to make such decisions for themselves,
>> but are you really sure?  If it were you receiving such
[quoted text clipped - 28 lines]
> I suppose this formality absolves you from second-guessing Takayuki?
> Yes, I am angry with you.

Me too, actually..and I admire Tak  reatly in bein  so restrained in his
reply.  I'm not sure I could have been in the same situation.  It is a
decision that can only be made by the care- iver.  I think we would all
agree /hey, the g is working again..\ that Tak will act in Betty's best
interest.  I would never dream of advising such as he about what to do.  He
will know, like we all do, if and when it is time to say no more.  That time
has not yet come IMHO.

((Tak & Betty))
Tweed
Adrian - 02 Sep 2005 19:49 GMT
>>> Well, everyone has to make such decisions for themselves,
>>> but are you really sure?  If it were you receiving such
[quoted text clipped - 40 lines]
> ((Tak & Betty))
> Tweed

I think it's time you got a new key board, fortunately they're not too
expensive.
Signature

Adrian (Owned by Snoopy & Bagheera)
A house is not a home, without a cat.
http://community.webshots.com/user/clowderuk

Christina Websell - 02 Sep 2005 20:17 GMT
>>>> Well, everyone has to make such decisions for themselves,
>>>> but are you really sure?  If it were you receiving such
[quoted text clipped - 43 lines]
> I think it's time you got a new key board, fortunately they're not too
> expensive.

I *had* a new keyboard.  To answer a ng query I reached for a book. A large
book.  Which caused the other books to topple over like dominoes and knock
over my Gallileo thermometer - which I really loved - down on to my
computer, where it smashed all over everything.
Spread oil just everywhere including over and in the keyboard :-( but a
friend has taken it away to see if he can clean it up and get it to work
again.  In the meantime, until I can get it back, I am using my old keyboard
from my '96 computer and the g seems to be working again!

Tweed
Adrian - 02 Sep 2005 20:28 GMT
>>>>> Well, everyone has to make such decisions for themselves,
>>>>> but are you really sure?  If it were you receiving such
[quoted text clipped - 54 lines]
>
> Tweed

I'm sorry to hear about the thermometer, I'm glad you've a spare
keyboard and can still use the computer.
Signature

Adrian (Owned by Snoopy & Bagheera)
A house is not a home, without a cat.
http://community.webshots.com/user/clowderuk

Jo Firey - 02 Sep 2005 22:20 GMT
>> I think it's time you got a new key board, fortunately they're not too
>> expensive.
[quoted text clipped - 9 lines]
>
> Tweed

Now wait a minute.  I had one of those thermometers.  Its supposed to be
sitting on that shelf over there.  And I don't remember when I saw it last.

That usually means the kids broke it and got rid of the evidence.  I hope
they had a really hard time cleaning it up!

Jo
Christina Websell - 02 Sep 2005 22:46 GMT
>>> I think it's time you got a new key board, fortunately they're not too
>>> expensive.
[quoted text clipped - 18 lines]
>
> Jo
<g>  So yours is gone too, is it?   Mine was only designed to work between
18-26C and I thought it might never work in my house because it's pretty
cold in here as a rule.  It never moved for ages until it got hot here.
Then suddenly it started to work.  The glass bubbles accurately reflected
the temperature, and it fascinated me.  I feel sad that it got broken, and
the place where I got it from don't have them now. <sigh>

Tweed
Jane - 06 Sep 2005 17:35 GMT
I *love* those thermometers and have always wanted one. I will forever
kick myself for not getting it a couple of years ago when they had them
at a good price at a warehouse store here. I (foolishly) hoped that
I might get one for Christmas that year.  Silly me. It's been YEARS
since I got anything that I actually wanted for Christmas.  Unless it's
something that I bought myself, that is.  
Next time I see one, it's MINE.

Jane
- owned and operated by Princess Rita

>>> and knock over my Gallileo thermometer - which I really loved - down on
>>> to my computer, where it smashed all over everything.
[quoted text clipped - 21 lines]
>
>Tweed
Christina Websell - 02 Sep 2005 19:02 GMT
>> Last night, I must have been in the bargaining phase of mourning,
>> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 60 lines]
> mere fact of "life" is more important than the quality of that life.
> Purrs and prayers for you and Betty, whatever you ultimately do.

I don't think that's a very fair thing to say.  There is a difference
between deciding on your own behalf and on behalf of another.  I had a dog
with squamous cell carcinoma of the face a few years ago.  I took all the
treatments for him that were available.  A referral to a professor of
veterinary oncology at a university many miles away, and we undertook the
chemotherapy that she recommended.   His tumour was in his lip and I had
already had it operated on and debulked before we were referred on.
I pursued any and all treatments that might help him, and do you know why?
Because it was *me* making decisions for *him* and had I not done so I would
have always had a lingering feeling of guilt that I didn't do everythin
(sorry my key has just stuck down, we'll have to do without the letter that
comes before h!) humanly possible to  ive him every chance.
I would ima ine that that's how Tak feels now, that every possibility of
cure must be looked into and I support him in this choice while Betty is so
well.
ood luck Tak and Betty! and many hugs to you both.

Tweed
Gabey8 - 02 Sep 2005 21:37 GMT
[[Well, everyone has to make such decisions for themselves,
but are you really sure?  If it were you receiving such
radical treatment, would you really WANT it?  (Personally, I
cannot imagine doing such a thing - I'd rather make my peace
with everyone and bow out with an overdose of something -
so of course I make the same decision for my pets, given
such a bleak prognosis.)  However, we're all different, and
for some of us the mere fact of "life" is more important
than the quality of that life.  Purrs and prayers for you
and Betty, whatever you ultimately do.]]

FWIW, I can empathize with Tak's decision to at least TRY available
treatments and see what'd work.

In my cat's case a few years ago, it was already known from the get-go
that Melody's case of thoracic lymphosarcoma was inoperable and incurable
by the time it showed any symptoms and was discovered. Palliative care
*could* buy quality time, but that was the best we could hope for.

At least three treatment options were available. But on discussing them
with the vet, I came to understand that all three would have about the
same efficacy. It wasn't a case where any one of the treatments would be
likely to be noticeably more useful than the others.

So I went with the least-invasive treatment. Where the original prognosis
was 3-6 months, Melody had quality time for 7 months. She really was her
normal self: eating, playing, demanding attention, purring her little head
off, being a lap fungus, etc. The vet was amazed that she did so well for
so long, maintaining her weight and her strength.

The end, when it came, didn't take long. She showed signs of illness, we
returned to the vet, and x-rays showed that the mass was SO large that
there was no treatment that could buy any more quality time.

I'd made a resolution when the cancer was first diagnosed that the day it
was certain that there would be no more quality time would be the day I
let go. So I requested the final act of mercy from the vet. Anyone who saw
that set of x-rays would have done the same. :o(

But I did have seven more months of Melody's priceless company... months I
wouldn't trade for anything. If treatment can buy quality time, and if the
pet's owner can afford to provide it, it's well worth the effort in my
book.

But if it's NOT providing quality time -- something that might only be
possible to determine by trying the treatment to see how the pet responds
to it -- then it's not fair to the pet.

FWIW, I can definitely understand why someone would at least try a
treatment to SEE if it works. Provided, that is, that they're willing to
be honest with themselves and if the pet has reached a point where it's
impossible to stave off their suffering anymore, that they're also willing
to do the unselfish thing and let go.

Tak, I wish the vets had been able to provide happier answers for you and
Betty. You're both in my prayers.

Donna, Captain, and Stanley
Howard C. Berkowitz - 02 Sep 2005 03:04 GMT
> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
> listening...

Hugs.

> I asked that Betty's life be spared.  In return, I offer my own life.
> A life for a life is fair, isn't it?  It's not that I don't love my
[quoted text clipped - 27 lines]
> type of cancer in some cases.  Betty can be given a prescription
> through an out-of-state pharmacy that does custom reformulations.

Nonsteroidal anti-inflammatory drugs (NSAID) are more and more used for
this, in two-legs and four-legs. If you have any problem finding a
compounding pharmacy, we do have a local one in Alexandria, Virginia --
I can get you the information if you need it.

This was along the lines of what I did for Clifford's bladder cancer.  
We used a combination of a nonsteroidal anti-inflammatory agent
(fluriprofen) and a corticosteroid, prednisone. These both relieve
discomfort and can shrink that type of tumor.

I found these easiest to administer as liquids (tuna-flavored) with a
syringe. If you have to give multiple drugs to Betty, even if the drugs
can't be mixed in the prescription, it's usually possible to draw them
sequentially into the syringe and give them all in one burst.

The hope had been that they could reduce the tumor sufficiently that he
would be strong enough to take more aggressive chemotherapy, which had
about a 30% chance of putting him into remission for up to a couple of
years. While I had some concerns about one of the chemotherapy drugs,
which has almost intolerable side effects in human, the oncologist
assured me that cats tolerate it (cisplatin) much better than humans.

In human cancer, there's been considerable work since then exploring the
NSAID family, and some of the new COX-2 inhibitors (e.g., Vioxx and
Celebrex) may be more effective than the nonselective NSAIDs.  This
isn't specific to bone cancer.

> So then he asked, what did I want to do?  The oncology center's custom
> is to describe the treatments possible, and give pet owners carte
[quoted text clipped - 5 lines]
> wanted to treat this as aggressively as is logical to do medically,
> and continue to escalate until I say stop.

This makes sense. I had to deal with my mother's bone metastases from
breast cancer, although there were far fewer options at the time.

> He understood.  So Betty will be starting on the anti-inflammatory
> drug, and going through a course of radiation, one treatment weekly
> for three weeks, after which the results will be observed, and we'll
> decide what to do next.  More radiation?  Chemotherapy, even though
> it's a long shot?

One of the problems of bone cancer can be that it will weaken the bone
and make fractures more likely. Some of the drugs now used for
osteoporosis are used to avoid this in humans, but don't know if they
have been used in cats. It's something to explore.

> The oncologist emphasized that he does not believe this cancer can be
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.

You made much the choice that I did. It's never perfect.
Takayuki - 02 Sep 2005 04:47 GMT
>This makes sense. I had to deal with my mother's bone metastases from
>breast cancer, although there were far fewer options at the time.

>You made much the choice that I did. It's never perfect.

It's hard to know 100% what to do when the doctor gives such a bleak
prognosis.  You're just a fountain of information!  It makes it easier
to see what the options are, and it helps me out that you have good
knowledge in these areas.

And thank you for the information about the anti-inflammatories - it's
very interesting.  Unfortunately, I didn't catch what the name of the
specific one they prescribed was, but they've sent the prescription to
a pharmacy in New Hampshire, so I'll be calling them tomorrow about it
to arrange pick up or delivery.
Victor Martinez - 02 Sep 2005 03:12 GMT
> The oncologist emphasized that he does not believe this cancer can be
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.

Tak, we're keeping you and Betty in our thoughts and we're sending lots
and lots of purrs. I can only begin to imagine how you must feel, having
had a false scare with Basho a while back.
Hang in there!

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Pat - 02 Sep 2005 03:21 GMT
I'll be praying that Betty's treatment is effective in a manner as yet
unheard of. In other words, a miraculous cure. It *can* happen.
Gennie - 02 Sep 2005 03:23 GMT
{{{{{{Tak}}}}}}   {{{{{{Betty}}}}}}

Gennie
Susan M - 02 Sep 2005 03:26 GMT
> I digested all this new information.  I thought about it.  What did I
> want for Betty?  Finally, I answered - I don't know whether the answer
> came from the mind or front the heart, but I answered.   I said that I
> wanted to treat this as aggressively as is logical to do medically,
> and continue to escalate until I say stop.

{{{{Tak and Betty}}}}

Susan M
Otis and Chester
Gabey8 - 02 Sep 2005 03:28 GMT
Purrs that you're able to help Betty have the maximum amount of quality
time possible.

Donna, Captain, and Stanley
Cheryl - 02 Sep 2005 03:58 GMT
On Thu 01 Sep 2005 09:21:12p, Takayuki wrote in
rec.pets.cats.anecdotes (news:018fh15l0rcrcmfrdf4vmg485ttn11esb5@
4ax.com):

> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
> listening...

Tak, I'm so sorry to read this news lately about your Betty. I know
you'll do whatever is right for her. You're both in my thoughts and
prayers.

Signature

Cheryl

"The clever cat eats cheese and breathes down rat holes with baited
breath."
- W.C. Fields

sriddles@aol.com - 02 Sep 2005 04:02 GMT
> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.

Sending all our purrs to Betty.

Sherry
Ann - 02 Sep 2005 04:06 GMT
Purrs for you and Betty.
Ann

Signature

read Sam's blog at http://kittens-3.blogspot.com/
see pictures of Sam at
http://pg.photos.yahoo.com/ph/ann791/my_photos

> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.
Shiral - 02 Sep 2005 04:10 GMT
What a hard choice!  I hope Betty's illness will at least be slowed by
her treatments.  
(((Takayuki)))

Melissa
Kreisleriana - 02 Sep 2005 04:21 GMT
>Last night, I must have been in the bargaining phase of mourning,
>because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 7 lines]
>current furry baby.  So her life is more important than mine.  Kill me
>in my sleep, I pleaded.
(snip)

Dumb idea, anyway, Tak.  Betty needs you.

Oh Tak, I really have no words.  We are *never* ready for this kind of
choice, and it seems especially cruel with such a special creature as
Betty.  Our thoughts and purrs are with you.

Theresa
Stinky Pictures: http://community.webshots.com/album/125591586JWEFwh
My Blog: http://www.humanitas.blogspot.com
Candace - 02 Sep 2005 04:27 GMT
> The oncologist emphasized that he does not believe this cancer can be
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.

I'm sorry. I hope it all works out and I hope she tolerates her
treatment well.

Candace
badwilson - 02 Sep 2005 04:33 GMT
I'm so sorry Tak.  Many purrs that the treatment is effective even
though the doc doesn't think so.  And don't offer up your life!  Who
would feed Betty?!?
--
Britta
"There is no snooze button on a cat who wants breakfast." -- Unknown
Check out pictures of Vino at:
http://photos.yahoo.com/badwilson click on the Vino album

> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.
Takayuki - 03 Sep 2005 03:42 GMT
>I'm so sorry Tak.  Many purrs that the treatment is effective even
>though the doc doesn't think so.  And don't offer up your life!  Who
>would feed Betty?!?

Oh, she'll be taken care of.  People here know about me and Betty, and
many of them are the pushy^H^H^H^H^Hproactive type.  So if they can't
contact me when they expect to, they'll probably kick down my door,
feed Betty, and scoop her box. :)
Christine Burel - 02 Sep 2005 04:51 GMT
(((((Takayuki)))) -- you and Betty are in our thoughts and purrayers.  I'm
so very sorry you and she are having to go through this.
Christine
> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.
Nomen Nescio - 02 Sep 2005 06:30 GMT
-----BEGIN PGP SIGNED MESSAGE-----

From: Takayuki <Takayuki9z@yahoo.com>

>I digested all this new information.  I thought about it.  What did I
>want for Betty?  Finally, I answered - I don't know whether the answer
>came from the mind or front the heart, but I answered.   I said that I
>wanted to treat this as aggressively as is logical to do medically,
>and continue to escalate until I say stop.

First, I want to say that I do feel for what you're going
through.
And second, I think you made the right decision. My feelings
in these situations is that you fight the disease as hard as
you can, with the best people, the best treatment, and the
best hope that you can come up with. Sometimes, you just
get lucky. And I've always thought that a prayer or two
can't hurt.
The group rec.pets.cats.health+behav seems to get a bad
rap around here, but I would also suggest the you post about
Betty's condition over there. There's a guy named "Phil P."
that follows the group who has been a true Godsend to me
when I found out that my big 'ol buddy "TK" had suddenly
developed a heart murmur that turned out to be moderate
Hypertrophic Cardiomyopathy. Phil isn't a vet, but he works
with a LOT of cats and seems, in many cases, to know more
that most vets.He went out of his way to look over TKs
echo report and explain in detail just what those 2 pages of
numbers all meant.
When TK was diagnosed in May, the cardiologist and the
report seemed to paint a pretty grim outlook. Phil looked
at things and said it doesn't look all that bad, to him. TK
had a regular checkup in August and the vet had to go get
the electronic stethoscope to hear even a trace of a heart
murmur (it was a 3+ on a scale of 6 back in May). Now I'm
hoping his echo in 2 months looks as good as the diminishing
murmur would indicate.
Anyway, if there's anything that you're iffy about, it wouldn't
hurt to run it by "Phil P." It might help you bring the whole picture
into focus.
My best wishes  for you and Betty.
Takayuki - 03 Sep 2005 03:47 GMT
>Anyway, if there's anything that you're iffy about, it wouldn't
>hurt to run it by "Phil P." It might help you bring the whole picture
>into focus.
>My best wishes  for you and Betty.

Thank you for the good advice.  Right now, I'm basically on schedule
to be at the oncology center every week, and I'm getting good
information, but if I have some more questions, or want second and
third opinions, I'll look for Phil on the newsgroup.
jmcquown - 02 Sep 2005 06:49 GMT
> So then he asked, what did I want to do?  The oncology center's custom
> is to describe the treatments possible, and give pet owners carte
[quoted text clipped - 15 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.

Oh, Tak, I'm so sorry to hear about this!  I'll definitely be asking for
some devine intervention on Betty's behalf.  Just please, hard as it is,
don't let her suffer.

Jill
Takayuki - 03 Sep 2005 03:48 GMT
>Oh, Tak, I'm so sorry to hear about this!  I'll definitely be asking for
>some devine intervention on Betty's behalf.  Just please, hard as it is,
>don't let her suffer.

This part is tough, and isn't something that I even considered before,
but it's something I'll have to think about very hard when the time
comes.
Krista - 02 Sep 2005 07:31 GMT
(snipped)

> The oncologist emphasized that he does not believe this cancer can be
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.

We are purring very, very hard for you and Betty.  I hope your Betty
confounds all prognoses, but I know that you will make the right
decisions for her, knowing how much you love her and how much
consideration you have always given to her needs.

((((((Tak))))))

------
Krista
Yoj - 02 Sep 2005 08:02 GMT
Purrs and purrayers for you and Betty.

Signature

Joy

> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.
Yowie - 02 Sep 2005 08:57 GMT
What a difficult choice you had to make! Purrs for Betty and yourself. I'm
sure with you as her guardian, her her quality of life will continue to be
good, no matter how long she has left with you.

Yowie

> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.
Exocat - 02 Sep 2005 09:48 GMT
> Firstly, Betty's cancer is inoperable,
> he said.  It has penetrated too much into the jaw.  A clean excision
[quoted text clipped - 10 lines]
> type of cancer in some cases.  Betty can be given a prescription
> through an out-of-state pharmacy that does custom reformulations.

So Sorry to learn this, even though it was expected. You & Betty have
our most supportive purrs & human best wishes for the treatments to
provide a good quality of life for as long as possible.  You will hear
Betty tell you when she'd like you to stop, I have no doubt.

Please keep us all posted. I'm sure everyone here (a few moronic
trollsters possibly excluded) will be right behind you every step of
the way.

Big Purrs

Gordon & the FF
Annie Wxill - 02 Sep 2005 13:19 GMT
> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 11 lines]
> who would there be to bother to fulfill such a wish anyway?  I felt
> silly to have even asked.

Tak,
My heart goes out to you and Betty.

You were not silly to have tried to strike such a bargain.  Your love for
Betty is an inspiration.

Just because we do not get what we ask for, it does not mean we have not
been heard.  It means that there is a bigger picture that we don't see.
If your wish had been granted, Betty would have had to live the rest of her
life without you.  Whenever those inevitable final days would come, who
would be there to give her the care and love you are giving her now?

I'm hoping that a miracle is in store, or at least you will have more time
with Betty.  And because you are here, I hope you will derive some peace in
knowing that she will continue to get the love and best care anyone could
provide during those terrible times when the decisions are so very
difficult.

We shared your joy, and we will share your tears.

Annie
Nan - 02 Sep 2005 14:06 GMT
>Last night, I must have been in the bargaining phase of mourning,
>because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
>cured.  But maybe its effects can be delayed.  She's going in for her
>first treatment on Wednesday.

{{{{{{{{{Betty & her worried daddy}}}}}}}}

Purrs and Hugs,

Nan
Pamela  Shirk - 04 Sep 2005 22:37 GMT
>>Last night, I must have been in the bargaining phase of mourning,
>>because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 53 lines]
>
> {{{{{{{{{Betty & her worried daddy}}}}}}}}

I did not get the original on this, so am stealing Nan's post as the
original.  Sorry Nan.

Tak, I'm so sorry that you're going through this, but so glad that Betty has
you to go through it with.  Does that make sense?  She is so lucky to have
someone who loves her so much to take care of her and make sure that she has
the best life she can have.  Needless to say, we're all here for you both
and hope that you two can have long and meaningful lives together.

We're sending all the purrs and healing thoughts we can in your direction.

Pam S.
Kate - 02 Sep 2005 15:03 GMT
{{Tak & Betty}}

Hope the treatment goes well, and exceeds expectations.

Lots of good thoughts and purrs from us here.

Hugs,
Kate

Owned by Fudge, Caramel & Meg.
Hazel Baker - 02 Sep 2005 16:23 GMT
To both of you ......sincere purrs.
                             Hazel

                                   
 
Adrian - 02 Sep 2005 16:58 GMT
<snip>
> The oncologist emphasized that he does not believe this cancer can be
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.

Continuing purrs that Betty has plenty of quality time left.
Signature

Adrian (Owned by Snoopy & Bagheera)
A house is not a home, without a cat.
http://community.webshots.com/user/clowderuk

Irulan - 02 Sep 2005 17:11 GMT
Tak, whatever you decide is the right decision. We are here for you to talk
to. We will purr and pray that Betty is comfortable and that you and she
spend a long time together happily.
Lily & her mama

Signature

Irulan
from the stars we come
to the stars we return
from now until the end of time

> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.
M Elizabeth - 02 Sep 2005 17:31 GMT
Huge hugs and purrs coming...
glsummer@neptunelink.com - 02 Sep 2005 18:42 GMT
>Last night, I must have been in the bargaining phase of mourning,
>because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
>cured.  But maybe its effects can be delayed.  She's going in for her
>first treatment on Wednesday.

{{{{Betty}}}}

I'm so sorry.  I hope that the treatments help her and that she can be
comfortable soon.

Blessings,

Ginger-lyn

Home Pages:
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 http://www.angelfire.com/folk/glsummer (homepage & cats)
 http://freepages.genealogy.rootsweb.com/~summer/index.htm (genealogy)
 http://www.movieanimals.bravehost.com/ (The Violence Against
                        Animals in Movies Website)
lal - 02 Sep 2005 20:28 GMT
> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
> listening...

<snip>

> The oncologist emphasized that he does not believe this cancer can be
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.

Purrs for you and Betty.

lal
Enfilade - 02 Sep 2005 21:35 GMT
But maybe its effects can be delayed.  She's going in for her
> > first treatment on Wednesday.

Many purrs for Betty.  As long as she is happy and content and able to
keep "being Betty," then you are doing the right thing for her.

--Fil
Helen Miles - 02 Sep 2005 20:31 GMT
"Takayuki" said...

> I digested all this new information.  I thought about it.  What did I
> want for Betty?  Finally, I answered - I don't know whether the answer
> came from the mind or front the heart, but I answered.///

{{{{HUGS, PRAYERS & PURRS}}}} to you and Betty for what will undoubtably
be a tough time ahead.

This is desperately sad news, but please know that we're keeping you
both in our thoughts.

Helen M, HRFL Tiger, Pandora, Cleo, Robbie and Thomasina. And the d*g
Bonnie.
PatM - 03 Sep 2005 03:50 GMT
I'll be waiting to hear how things go, Tak.  Gentle hugs to you and
dear Betty.

PatM
Takayuki - 03 Sep 2005 04:20 GMT
>I'll be waiting to hear how things go, Tak.  Gentle hugs to you and
>dear Betty.
>
>PatM

I'll be sure to post about any significant or interesting
developments.  There's an evaluation scheduled immediately before the
third radiation treatment on 9/20, so I'll at least have to report the
findings from that.

It's sometimes been a bit hard to post about Betty though.  Her
condition scares me so much that worrying about it can make me
non-functional.  I have to force myself into a strange, detached state
of mind in order to be able to post about Betty without worrying too
much about her at the same time!
Marina - 03 Sep 2005 08:42 GMT
> It's sometimes been a bit hard to post about Betty though.  Her
> condition scares me so much that worrying about it can make me
> non-functional.  I have to force myself into a strange, detached state
> of mind in order to be able to post about Betty without worrying too
> much about her at the same time!

I know exactly what you mean, Tak. {{{{Tak and Betty}}}}

Signature

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marina (dot) kurten (at) iki (dot) fi
Pics at http://uk.pg.photos.yahoo.com/ph/frankiennikki/
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Marina - 03 Sep 2005 04:02 GMT
> The oncologist emphasized that he does not believe this cancer can be
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.

I hope the doc is wrong. We will be purring hard for you both from now
until then, and then on. I'm so sorry this had to happen to Betty.

Signature

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marina (dot) kurten (at) iki (dot) fi
Pics at http://uk.pg.photos.yahoo.com/ph/frankiennikki/
and http://community.webshots.com/user/frankiennikki

Sam Nash - 03 Sep 2005 23:44 GMT
>> The oncologist emphasized that he does not believe this cancer can be
>> cured.  But maybe its effects can be delayed.  She's going in for her
>> first treatment on Wednesday.
>
> I hope the doc is wrong. We will be purring hard for you both from now
> until then, and then on. I'm so sorry this had to happen to Betty.

I, too, hope the vet is wrong in this case.  Adding Mistletoe's and Smokey's
purrs and my prayers for Betty and for you.
Sam
polonca12000 - 03 Sep 2005 13:23 GMT
I'm so so sorry to hear this, Tak. I do so wish there was something I could
do.
We are purring and hoping for a miracle cure for Betty. You both are in our
thoughts,
Signature

Polonca & Soncek

> Last night, I must have been in the bargaining phase of mourning,
> because I made a plea to whoever might be listening, if anyone was
[quoted text clipped - 51 lines]
> cured.  But maybe its effects can be delayed.  She's going in for her
> first treatment on Wednesday.
Monique Y. Mudama - 04 Sep 2005 17:32 GMT
> So today, Betty saw the oncologist.  He examined her and told me
> about the nature of the cancer that Betty had.  I was impressed by
[quoted text clipped - 6 lines]
> of the jaw.  Cats invariably do not adapt to this, he said, and stop
> eating, although this option works fairly well on dogs.

Oh no ... I haven't been able to check RPCA much lately, so I didn't
know that Betty was ill.  I'm so sorry.  I hope that the aggressive
treatment allows you the time to share many more happy moments.

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pictures: http://www.bounceswoosh.org/rpca

 
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